Division of Gastroenterology/Hepatology, Digestive Health Center, Medical College of Georgia, Augusta University, Augusta, Georgia, USA.
Division of Gastroenterology, Mayo Clinic, Jacksonville, Florida, USA.
Am J Gastroenterol. 2022 Nov 1;117(11):1753-1758. doi: 10.14309/ajg.0000000000001945. Epub 2022 Aug 12.
Constipation is a common problem, affects 15% of the population, and is often self-diagnosed and self-managed. Over the past 3 decades, there have been significant advances in our understanding and management of chronic constipation, with the emerging recognition that occasional constipation (OC) is another subtype that falls outside current classifications. The purpose of this review was to describe the process of developing and proposing a new definition for OC based on expert consensus and taking into consideration the multifactorial nature of the problem such as alterations in bowel habit that include stool frequency and difficulty with stool passage, perception of the sufferer, duration of symptoms, and potential responsiveness to treatment. Leading gastroenterologists from 5 countries met virtually on multiple occasions through an online digital platform to discuss the problem of OC and recommended a practical, user-friendly definition: "OC can be defined as intermittent or occasional symptomatic alteration(s) in bowel habit. This includes a bothersome reduction in the frequency of bowel movements and/or difficulty with passage of stools but without alarming features. Bowel symptoms may last for a few days or a few weeks, and episodes may require modification of lifestyle, dietary habits and/or use of over-the-counter laxatives or bulking agents to restore a satisfactory bowel habit." Prospective studies are required to validate this definition and determine OC prevalence in the community. This review highlights current knowledge gaps and could provide impetus for future research to facilitate an improved understanding of OC and development of evidence-based management guidelines.
便秘是一种常见的问题,影响了 15%的人口,并且通常是自我诊断和自我管理的。在过去的 30 年中,我们对慢性便秘的理解和管理取得了重大进展,人们逐渐认识到偶发性便秘(OC)是另一种不在当前分类范围内的亚型。本综述的目的是描述根据专家共识为 OC 制定和提出新定义的过程,并考虑到该问题的多因素性质,例如包括粪便频率和排便困难在内的排便习惯改变、患者的感知、症状持续时间以及对治疗的潜在反应性。来自 5 个国家的领先胃肠病学家通过在线数字平台多次进行虚拟会议,讨论 OC 问题,并推荐了一个实用且易于使用的定义:“OC 可以定义为间歇性或偶发性的肠习惯症状改变。这包括排便频率明显减少和/或排便困难,但没有令人担忧的特征。肠道症状可能持续几天或几周,并且发作可能需要改变生活方式、饮食习惯和/或使用非处方泻药或膨松剂来恢复满意的肠道习惯。”需要前瞻性研究来验证该定义并确定社区中的 OC 患病率。本综述强调了当前的知识差距,并为未来的研究提供了动力,以促进对 OC 的更好理解和基于证据的管理指南的制定。