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毛发角化病治疗:干预研究证据。

Keratosis Pilaris Treatment: Evidence from Intervention Studies.

机构信息

Research and Education Unit, Centro Dermatológico "Dr. Ladislao de la Pascua," Mexico City, Mexico.

Research and Education Unit, Centro Dermatológico "Dr. Ladislao de la Pascua," Mexico City, Mexico;

出版信息

Skinmed. 2022 Aug 31;20(4):258-271. eCollection 2022.

Abstract

Keratosis pilaris is a common dermatosis observed in daily dermatologic practice. The diagnosis is clinical and usually asymptomatic, although sometimes patients may complain of mild pruritus and its cosmetic appearance. Few reports exist about its treatment. There are clinical trials assessing topical treatments and laser surgery, but no systematic reviews on its management were found in literature. An online research was conducted to identify evidence-based recommendations. Lactic acid, salicylic acid, and the 1064-nm Nd:YAG laser seem to be the most effective and safe treatment options for keratosis pilaris among patients aged 12 years and older; however, high-quality randomized controlled trials with long-term outcomes are required. (. 2022;20:258-271).

摘要

毛发角化病是日常皮肤科实践中常见的一种皮肤病。其诊断基于临床表现,通常无症状,但有时患者可能会主诉轻度瘙痒和皮肤外观不佳。目前已有关于其治疗的少数报道。有临床试验评估了局部治疗和激光手术,但文献中未发现关于其治疗的系统评价。进行了一项在线研究,以确定基于证据的推荐意见。对于 12 岁及以上的患者,乳酸、水杨酸和 1064nmNd:YAG 激光似乎是治疗毛发角化病最有效和安全的选择;然而,需要高质量的、具有长期结局的随机对照试验。(. 2022;20:258-271)。

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