Department of Plastic Surgery, PGIMER, Chandigarh, India.
Cleft Palate Craniofac J. 2024 Jan;61(1):126-130. doi: 10.1177/10556656221121044. Epub 2022 Aug 17.
Palatal fistulae are challenging complications following cleft palate repair. The addition of acellular dermal matrix (ADM) to cleft palate repair has been shown to reduce fistula formation in previous studies. The use of autologous dermal graft has all the structural advantages of ADM, has less rejection and immunogenic potential, and is cost effective. A prospective study. Patients with Group II and III cleft palate (Nagpur Classification) without prior intervention for palatal repair in the Department of Plastic Surgery at PGIMER from January 2020 till June 2021. The addition of autologous dermal graft for palatoplasty. Outcome of the study was fistula development or exposure of dermal graft. Autologous dermal graft was harvested of average dimension of 8.73 cm (range 5.25-18 cm) from groin region. Sixteen patients were included in the study. Among them, 2 patients (12.5%) developed postoperative fistula (Type III &V Pittsburgh Classification). Our study showed that the rates of postoperative fistula formation are comparable with prior literature using artificial dermal matrices.
腭裂修复术后出现腭瘘是一个具有挑战性的并发症。既往研究表明,在腭裂修复中添加脱细胞真皮基质(ADM)可减少瘘的形成。使用自体真皮移植物具有 ADM 的所有结构优势,排斥和免疫原性潜在风险更小,且具有成本效益。一项前瞻性研究。2020 年 1 月至 2021 年 6 月,在 PGIMER 整形外科学系,纳入无腭裂修复史的 II 类和 III 类腭裂(Nagpur 分类)患者。在腭裂修复中添加自体真皮移植物。研究的结果是瘘的形成或真皮移植物暴露。从腹股沟区域采集平均尺寸为 8.73cm(范围 5.25-18cm)的自体真皮移植物。本研究纳入了 16 名患者。其中,2 名患者(12.5%)出现术后瘘(匹兹堡分类 III 型和 V 型)。我们的研究表明,术后瘘的形成率与使用人工真皮基质的既往文献相似。