母亲声音对早产儿经口喂养比例的影响。
Effect of maternal voice on proportion of oral feeding in preterm infants.
作者信息
Chhikara Aditya, Hagadorn James I, Lainwala Shabnam
机构信息
Division of Neonatology, Connecticut Children's, Hartford, CT, USA.
Department of Pediatrics, University of Connecticut School of Medicine, Farmington, CT, USA.
出版信息
J Perinatol. 2023 Jan;43(1):68-73. doi: 10.1038/s41372-022-01493-4. Epub 2022 Aug 18.
OBJECTIVE
To determine the impact of maternal voice exposure on oral feeding in preterm infants.
STUDY DESIGN
Prospective, unblinded, 2-center intervention study of infants born 28 0/7-34 6/7 weeks gestation. Infants were exposed twice daily to maternal voice for 20 min before attempting oral feeding. Feedings were divided into groups consisting of Baseline, Intervention, and Follow-up feeds. The study was registered at clinicaltrials.gov (NCT05181020).
RESULT
29/37 (78%) mother-infant dyads consented for the study. 25 infants with 2051 feedings were included. Compared to the preceding Baseline, Intervention feeds were associated with an adjusted 7.1 percentage-point increase in oral intake (p = 0.036) and in post-hoc analysis a 71% increased likelihood of having the highest feeding readiness score (p = 0.003).
CONCLUSION
Exposure to maternal voice prior to enteral feeding is feasible and was associated with significantly improved oral feeding proportions in preterm infants.
CLINICAL TRIAL REGISTRY
clinicaltrials.gov (NCT05181020).
目的
确定母亲声音暴露对早产儿经口喂养的影响。
研究设计
对孕周为28⁰/₇ - 34⁶/₇周的婴儿进行的前瞻性、非盲法、2中心干预研究。在尝试经口喂养前，婴儿每天两次暴露于母亲声音中20分钟。喂养分为基线、干预和随访喂养组。该研究已在clinicaltrials.gov注册（NCT05181020）。
结果
29/37（78%）母婴对同意参与研究。纳入了25名婴儿的2051次喂养。与之前的基线相比，干预喂养的经口摄入量调整后增加了7.1个百分点（p = 0.036），在事后分析中，喂养准备度得分最高的可能性增加了71%（p = 0.003）。
结论
在肠内喂养前暴露于母亲声音是可行的，并且与早产儿经口喂养比例的显著改善相关。
临床试验注册
clinicaltrials.gov（NCT05181020）。
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