School of Chemical Science and Technology, Yunnan University, Kunming 650091, China.
State Key Laboratory for Conservation and Utilization of Bio-resources in Yunnan, Yunnan University, Kunming 650091, China.
Bioelectrochemistry. 2022 Dec;148:108248. doi: 10.1016/j.bioelechem.2022.108248. Epub 2022 Aug 17.
In this study, the corrosion behavior and mechanism of Ti-6Al-4V in artificial saliva with Candida albicans were investigated using electrochemical and surface analysis techniques. Fluorescence microscopy (FM) and confocal laser scanning microscopy (CLSM) showed that C. albicans could easily adsorb on the surface of Ti-6Al-4V alloy to form non-dense biofilm. The non-compact biofilm provided necessary conditions for pitting corrosion on Ti-6Al-4V alloys by scanning electron microscopy (SEM) observation. The potentiodynamic polarization (PDP) curves and electrochemical impedance spectroscopy (EIS) revealed that C. albicans significantly reduced the corrosion resistance of Ti-6Al-4V alloys. The cyclic voltammetry (CV) and differential pulse voltammetry (DPV) results indicated that C. albicans biofilm promoted electron transfer from the anodic sites to cathodic depolarizer during the corrosion process, showing that the role of oral fungi must be considered when evaluating the performance of oral materials. This study may provide a new clue for evaluating the corrosion resistance of dental implant materials in the oral environment.
在这项研究中，使用电化学和表面分析技术研究了 Ti-6Al-4V 在含有白色念珠菌的人工唾液中的腐蚀行为和机理。荧光显微镜（FM）和共聚焦激光扫描显微镜（CLSM）显示，白色念珠菌可以很容易地吸附在 Ti-6Al-4V 合金表面形成非致密的生物膜。非致密的生物膜通过扫描电子显微镜（SEM）观察为 Ti-6Al-4V 合金的点蚀腐蚀提供了必要的条件。动电位极化（PDP）曲线和电化学阻抗谱（EIS）表明，白色念珠菌显著降低了 Ti-6Al-4V 合金的耐腐蚀性。循环伏安法（CV）和差分脉冲伏安法（DPV）结果表明，在腐蚀过程中，白色念珠菌生物膜促进了从阳极位点到阴极去极化剂的电子转移，这表明在评估口腔材料的性能时必须考虑口腔真菌的作用。这项研究可能为评估口腔环境中牙科植入材料的耐腐蚀性提供新线索。
