脉络膜骨瘤合并脉络膜新生血管膜的抗血管内皮生长因子治疗：罕见病例并文献复习。
Choroidal Osteoma with Choroidal Neovascular Membrane treated with Anti- vascular Endothelial Growth Factor: A Rare Case with Review of Literatures.
机构信息
Gyalyum Kesang Choeden Wangchuck National Eye Centre, Thimphu, Bhutan.
出版信息
Nepal J Ophthalmol. 2021 Jul;13(24):196-201. doi: 10.3126/nepjoph.v13i2.33218.
INTRODUCTION
Choroidal osteoma, usually unilateral, is a rare benign tumor of choroid. It is predominantly seen in young females.
CASE
We report a case of a 35-year-old female with unilateral choroidal osteoma associated with choroidal neovascular membrane (CNVM). The diagnosis was confirmed with clinical examination, ocular ultrasonography, fundus fluorescein angiography and macular optical coherence tomography. Choroidal neovascular membrane improved with 3 doses of bevacizumab, an anti-vascular endothelial growth factors (Anti-VEGF).
CONCLUSION
Anti-VEGF monotherapy can be a cost effective primary modality of treatment for choroidal neovascular membrane secondary to choroidal osteoma.
介绍
脉络膜骨瘤，通常为单侧，是一种罕见的脉络膜良性肿瘤。它主要发生在年轻女性中。
病例
我们报告了一例 35 岁女性单侧脉络膜骨瘤伴脉络膜新生血管膜（CNVM）。诊断通过临床检查、眼部超声、眼底荧光血管造影和黄斑光学相干断层扫描得到确认。脉络膜新生血管膜经 3 次贝伐单抗（一种抗血管内皮生长因子（Anti-VEGF）药物）治疗后得到改善。
结论
抗 VEGF 单药治疗可能是脉络膜骨瘤继发脉络膜新生血管膜的一种具有成本效益的一线治疗方式。
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