Acta Orthop Belg. 2022 Jun;88(2):217-221. doi: 10.52628/88.2.8784.
The aim of the study is to find the correlation between vitamin D level and the severity of slippage and bilateral development in slipped capital femoral epiphysis (SCFE) cases if any. Thirty-nine patients with moderate-severe stable SCFE were evaluated regarding their vitamin D level and to which extent the severity of vitamin D deficiency, if present, can be correlated with the severity and bilaterality of the slip. Vitamin D serum level was assessed pre- operatively for all patients. In case of deficiency, the patient underwent in situ pinning unless performed before his/her presentation. Alongside, he/she received a vitamin D course until correction prior to the definitive surgery (Imhäuser osteotomy with osteochondroplasty) 6-12 weeks after. Thereafter, osteotomy healing and physis closure were monitored radiologically. Results show that all patients but one had vitamin D deficiency, with an average of 14.39 ng/mL, necessitating vitamin D therapy before proceeding to the definitive surgery. No correlation existed between vitamin D level and Southwick angle severity with a p-value of 0.85. A negative correlation existed between vitamin D level and bilaterality, but not statistically significant (p-value 0.192). Patients' osteotomy healing was uneventful, and physeal closure was achieved in all the cases that had in situ pinning. We conclude that the severity of Vitamin D deficiency could be linked to the bilateral development of SCFE but not the severity of slippage. Treatment of Vitamin D deficiency facilitates physeal closure.
本研究旨在探讨维生素 D 水平与股骨颈骨骺滑脱(SCFE)病例滑脱严重程度和双侧发展之间的相关性(如果存在的话)。对 39 例中重度稳定型 SCFE 患者进行了维生素 D 水平评估,以及维生素 D 缺乏的严重程度,如果存在,与滑脱的严重程度和双侧性之间的相关性。所有患者均在术前评估了维生素 D 血清水平。如果存在缺乏,患者在接受原位钉固定术(除非在其就诊前已进行)。同时,患者接受维生素 D 治疗,直到在确定性手术(伊马豪尔截骨术伴骨软骨成形术)前纠正。6-12 周后,进行。然后,通过放射学监测截骨愈合和骨骺闭合。结果显示,除 1 例患者外,所有患者均有维生素 D 缺乏,平均为 14.39ng/ml,在进行确定性手术前需要接受维生素 D 治疗。维生素 D 水平与 Southwick 角严重程度之间无相关性,p 值为 0.85。维生素 D 水平与双侧性之间存在负相关,但无统计学意义(p 值为 0.192)。患者的截骨愈合顺利,接受原位钉固定的所有病例均实现了骨骺闭合。我们得出结论,维生素 D 缺乏的严重程度可能与 SCFE 的双侧发展有关,但与滑脱的严重程度无关。维生素 D 缺乏的治疗有助于骨骺闭合。