Institute of Psychology, University of Wrocław, 50-527 Wrocław, Poland.
Nutrients. 2022 Aug 22;14(16):3447. doi: 10.3390/nu14163447.
Irritable bowel syndrome (IBS), as a functional and psychosomatic disease, reduces the quality of life and increases the risk of developing mental disorders. Deregulation of the autonomic nervous system (ANS) is one of the main causes of the disease. The objective of the present study was to identify the studies in which measurements of heart rate variability (HRV) were performed before and after therapeutic intervention, and to evaluate the effectiveness of IBS therapy in terms of a reduction of IBS symptoms and changes in autonomic tone. A systematic review of the literature was carried out in accordance with PRISMA standards. Six databases were searched for articles published before 2022: PubMed, MEDLINE, EBSCO, Cochrane, Scopus, and Web of Science. Inclusion criteria were experimental design, diagnosis of IBS (medical and/or diagnosis in accordance with the Rome Criteria), non-pharmacological intervention, and HRV measurement before and after the intervention. The quality of the studies was assessed by JBI Critical appraisal. In total, 455 studies were identified, of which, sixwere included in the review. Expected changes in HRV (increase in parasympathetic activity) were observed in four of the six studies (interventions studied: ear acupressure, transcutaneous auricular vagusnerve stimulation, cognitive behavioral therapy with relaxation elements, yoga). In the same studies, therapeutic interventions significantly reduced the symptoms of IBS. The present review indicated that interventions under investigation improve the efficiency of the ANS and reduce the symptoms of IBS. It is advisable to include HRV measurements as a measure of the effectiveness of interventions in IBS therapy, and to assess autonomic changes as a moderator of the effectiveness of IBS therapy.
肠易激综合征（IBS）作为一种功能性和身心疾病，降低了生活质量并增加了发展精神障碍的风险。自主神经系统（ANS）失调是疾病的主要原因之一。本研究的目的是确定在治疗干预前后进行心率变异性（HRV）测量的研究，并根据 IBS 症状的减轻和自主神经张力的变化来评估 IBS 治疗的效果。根据 PRISMA 标准进行了系统的文献回顾。在 2022 年之前，在六个数据库中搜索了发表的文章：PubMed、MEDLINE、EBSCO、Cochrane、Scopus 和 Web of Science。纳入标准为实验设计、IBS 诊断（医学和/或符合罗马标准的诊断）、非药物干预和干预前后的 HRV 测量。研究质量由 JBI 批判性评估进行评估。总共确定了 455 项研究，其中 6 项研究被纳入综述。在六项研究中的四项研究中观察到 HRV 的预期变化（副交感神经活动增加）（研究的干预措施：耳压、经皮耳迷走神经刺激、放松元素的认知行为疗法、瑜伽）。在相同的研究中，治疗干预显著减轻了 IBS 的症状。本综述表明，正在研究的干预措施改善了 ANS 的效率并减轻了 IBS 的症状。建议将 HRV 测量作为 IBS 治疗中干预效果的衡量标准，并评估自主神经变化作为 IBS 治疗效果的调节剂。
