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脑性瘫痪成人骨折后康复途径与死亡率的关系。

Post-fracture rehabilitation pathways and association with mortality among adults with cerebral palsy.

机构信息

Department of Physical Medicine and Rehabilitation, 1259University of Michigan, Ann Arbor, MI, USA.

Institute for Healthcare Policy and Innovation, 1259University of Michigan, Ann Arbor, MI, USA.

出版信息

Clin Rehabil. 2023 Jan;37(1):119-131. doi: 10.1177/02692155221123544. Epub 2022 Aug 29.

DOI:10.1177/02692155221123544
PMID:36039504
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10150496/
Abstract

OBJECTIVE

Rehabilitation may mitigate the high mortality rates and health declines post-fracture for adults with cerebral palsy, but this is understudied. The objectives were to characterize the post-fracture rehabilitation pathways and identify their association with 1-year survival among adults with cerebral palsy.

METHODS

A retrospective cohort study of adults with cerebral palsy with a fragility fracture with continuous health plan enrollment ≥1-year prior to and ≥1 day after their fracture date was performed using a random 20% Medicare fee-for-service dataset. Participants were categorized as a home discharge or inpatient rehabilitation admission post-fracture. For the home discharge cohort, weekly exposure to outpatient physical/occupational therapy (PT/OT) was examined up to 6-month post-fracture. Cox regression examined the association between time-varying PT/OTuse within 6-month post-fracture and mortality from 30 days to 1-year post-fracture before and after adjusting for confounders (e.g. medical complexity).

RESULTS

Of 3598 adults with cerebral palsy with an incident fragility fracture, 74% were discharged home without inpatient rehabilitation; they were younger, but more medically complex compared to the 26% admitted to inpatient rehabilitation. Among the home discharge cohort (n = 2662), 43.1% initiated PT/OTwithin 6-month post-fracture, and cumulative PT/OTexposure post-fracture was associated with improved survival; for example, per 3 weeks of PT/OTexposure, the adjusted mortality rate was 40% lower (95% confidence interval (CI) = 0.41-0.89).

CONCLUSIONS

Most adults with cerebral palsy with a fragility fracture were discharged home rather than to inpatient rehabilitation, and only 43.1% of that group initiated outpatient PT/OTwithin 6 months post-fracture. Receiving outpatient PT/OTwas associated with improved 1-year survival.

摘要

目的

康复治疗可能减轻脑瘫成年人骨折后的高死亡率和健康状况下降,但这方面的研究还很不足。本研究旨在描述骨折后康复途径,并确定其与脑瘫成年人 1 年生存率的关系。

方法

采用 20%的随机 Medicare 按服务项目付费数据集,对有脆性骨折且骨折前 1 年和骨折后 1 天连续有医疗保险计划参保的脑瘫成年人进行回顾性队列研究。患者骨折后被分为出院回家或住院康复治疗。对于出院回家的患者,在骨折后 6 个月内,每周检查门诊物理治疗/职业治疗(PT/OT)的暴露情况。Cox 回归分析了骨折后 6 个月内 PT/OT 治疗的时间变化与骨折后 30 天至 1 年死亡率之间的关系,该分析在调整混杂因素(如医疗复杂性)前后分别进行。

结果

在 3598 例有脆性骨折的脑瘫成年人中,74%出院回家,没有接受住院康复治疗;与接受住院康复治疗的 26%患者相比,这些患者年龄较小,但医疗复杂性更高。在出院回家的患者中(n=2662),43.1%在骨折后 6 个月内开始接受 PT/OT 治疗,骨折后接受的 PT/OT 治疗与生存率提高有关;例如,PT/OT 治疗每增加 3 周,调整后的死亡率降低 40%(95%置信区间(CI)为 0.41-0.89)。

结论

大多数有脆性骨折的脑瘫成年人出院回家,而非住院康复治疗,其中只有 43.1%的患者在骨折后 6 个月内开始接受门诊 PT/OT 治疗。接受门诊 PT/OT 治疗与 1 年生存率提高有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/80bc/10150496/159e4751f36c/nihms-1891005-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/80bc/10150496/6f484faf9ce5/nihms-1891005-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/80bc/10150496/159e4751f36c/nihms-1891005-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/80bc/10150496/6f484faf9ce5/nihms-1891005-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/80bc/10150496/159e4751f36c/nihms-1891005-f0002.jpg

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Ann Phys Rehabil Med. 2022 Nov;65(6):101661. doi: 10.1016/j.rehab.2022.101661. Epub 2022 Apr 28.
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Bone. 2022 Jun;159:116390. doi: 10.1016/j.bone.2022.116390. Epub 2022 Mar 17.
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Critical periods of bone health across the lifespan for individuals with cerebral palsy: Informing clinical guidelines for fracture prevention and monitoring.
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