Meinel H, Ihle R, Laschinski M
Zentralbl Gynakol. 1987;109(8):527-31.
During a period of observation of one year blood pressure was measured three times in the 0,6 th and 12 th months from a group of users of oral contraceptives (n = 377) and a reference group (n = 238) dependent from pregnancy-induced hypertension in women's history. Mean systolic blood pressure dropped in the group of oral contraceptive users by 0.7 mm Hg (0.1 kPa), diastolic blood pressure increased by 2.1 mm Hg (0.3 kPa) with significant difference vs. the reference group. Mean systolic blood pressure increased by 1.7 mm Hg (0.22 kPa) 6 months after using oral contraceptives in the group with pregnancy-induced hypertension (with significant difference). In the reference group without pregnancy-induced hypertension mean systolic blood pressure increased by 1.5 mm Hg (0.2 kPa) (without significant difference). Diastolic blood pressure values were not different. In the subgroup with pregnancy-induced hypertension history basal values of systolic and diastolic blood pressure distinctly were higher than in the control group.
在为期一年的观察期内,对一组口服避孕药使用者(n = 377)和一个参照组(n = 238)(后者因女性既往有妊娠高血压病史而入选)在第0、6和12个月时测量了三次血压。口服避孕药使用者组的平均收缩压下降了0.7毫米汞柱(0.1千帕),舒张压升高了2.1毫米汞柱(0.3千帕),与参照组相比有显著差异。有妊娠高血压病史的组在使用口服避孕药6个月后平均收缩压升高了1.7毫米汞柱(0.22千帕)(有显著差异)。在无妊娠高血压病史的参照组中,平均收缩压升高了1.5毫米汞柱(0.2千帕)(无显著差异)。舒张压值无差异。在有妊娠高血压病史的亚组中,收缩压和舒张压的基础值明显高于对照组。