Toure Abdoulaye, Camara Saidouba Cherif, Camara Alioune, Conde Mamoudou, Delamou Alexandre, Camara Ibrahima, Bangoura Salifou Talassone, Camara Alimou, Diallo Mamadou Bobo, Keita Mamadou Bhoye, Kourouma Kaba, Camara Robert, Etard Jean-Francois, Keita Alpha-Kabinet
Centre de Recherche et de Formation en Infectiologie de Guinée (CERFIG), Université Gamal Abdel Nasser, Conakry, Guinea.
Chaire de Santé Publique, Université Gamal Abdel Nasser de Conakry, Conakry, Guinea.
J Public Health Afr. 2022 Jul 26;13(2):2082. doi: 10.4081/jphia.2022.2082.
Data regarding the prevalence and consequences of self-medication during the COVID-19 pandemic in Africa are very limited. The study aimed to explore the frequency and risk factors of self-medication against COVID-19 by health personnel in this study. This cross-sectional study took place in June 2021, in Conakry, in the all three national hospitals and the six community medical centers, and five primary health centers. A multivariate logistic regression model was performed to identify factors associated with self-medication. A total of 975 health workers with a median age of 31 (IQR: 27-40) years, with 504 (51.7%) women were included. The majority were clinicians: physicians (33.1%) or nurses (33.1%). Of all, 46.2% reported having had at least one COVID-19 symptom during the 12 months preceding the survey. The proportion of self-medication was 15.3% among national hospital staff, 12.20% in municipality medical centers and 22.6% in primary health centers (p=0.06). More than two-thirds (68.7%) who selfmedicated did not have a test for SARSCoV- 2 infection. They took antibiotics including azithromycin, amoxicillin, ampicillin (42.2%), acetaminophen (37.4%), vitamin C (27.9%), hydroxychloroquine (23.8%) and medicinal plants (13.6%). The median duration of self-medication was 4 days. Fatigue or asthenia, sore throat, loss of smell and sore throat of a close person were independently associated with selfmedication. Health care workers largely practiced self-medication during the Covid pandemic and without diagnostic testing. The results suggest the need for training and sensitization of medical personnel to avoid the consequences of the molecules used, including hepatotoxicity and antibiotic resistance.
关于非洲新冠疫情期间自我药疗的患病率及后果的数据非常有限。本研究旨在探讨本研究中卫生人员针对新冠进行自我药疗的频率及风险因素。这项横断面研究于2021年6月在科纳克里的所有三家国立医院、六个社区医疗中心和五个初级卫生中心开展。采用多变量逻辑回归模型来确定与自我药疗相关的因素。共纳入975名卫生工作者，中位年龄为31岁（四分位间距：27 - 40岁），其中504名（51.7%）为女性。大多数是临床医生：医生（33.1%）或护士（33.1%）。在所有人员中，46.2%报告在调查前12个月内至少出现过一种新冠症状。国立医院工作人员的自我药疗比例为15.3%，市医疗中心为12.20%，初级卫生中心为22.6%（p = 0.06）。超过三分之二（68.7%）进行自我药疗的人未进行新冠病毒感染检测。他们服用的药物包括阿奇霉素、阿莫西林、氨苄西林等抗生素（42.2%）、对乙酰氨基酚（37.4%）、维生素C（27.9%）、羟氯喹（23.8%）和药用植物（13.6%）。自我药疗的中位持续时间为4天。疲劳或乏力、喉咙痛、嗅觉丧失以及亲密接触者喉咙痛与自我药疗独立相关。在新冠疫情期间，医护人员大量进行自我药疗且未进行诊断检测。结果表明需要对医务人员进行培训并提高其认识，以避免所使用药物带来的后果，包括肝毒性和抗生素耐药性。
