Meyer J S, Ishikawa Y, Hata T, Karacan I
Brain Cogn. 1987 Jul;6(3):266-94. doi: 10.1016/0278-2626(87)90127-8.
Measurements of regional or local cerebral blood flow (CBF) by the xenon-133 inhalation method and stable xenon computerized tomography CBF (CTCBF) method were made during relaxed wakefulness and different stages of REM and non-REM sleep in normal age-matched volunteers, narcoleptics, and sleep apneics. In the awake state, CBF values were reduced in both narcoleptics and sleep apneics in the brainstem and cerebellar regions. During sleep onset, whether REM or stage I-II, CBF values were paradoxically increased in narcoleptics but decreased severely in sleep apneics, while in normal volunteers they became diffusely but more moderately decreased. In REM sleep and dreaming CBF values greatly increased, particularly in right temporo-parietal regions in subjects experiencing both visual and auditory dreaming.
采用氙-133吸入法和稳定氙计算机断层扫描脑血流量（CTCBF）法，对年龄匹配的正常志愿者、发作性睡病患者和睡眠呼吸暂停患者在清醒放松状态以及快速眼动（REM）睡眠和非快速眼动睡眠的不同阶段进行局部或区域脑血流量（CBF）测量。在清醒状态下，发作性睡病患者和睡眠呼吸暂停患者脑干和小脑区域的CBF值均降低。在睡眠开始时，无论是REM睡眠还是I-II期，发作性睡病患者的CBF值反而升高，而睡眠呼吸暂停患者的CBF值则严重降低，正常志愿者的CBF值则呈弥漫性但程度较轻的降低。在REM睡眠和做梦时，CBF值大幅升高，尤其是在经历视觉和听觉梦境的受试者的右侧颞顶叶区域。
