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新冠病毒感染后出现肿胀性脱髓鞘病变,用β-干扰素1A成功治疗。

Tumefactive demyelination after covid-19 successfully treated with betainterferon 1A.

作者信息

Araújo Victor Oliveira, Marcelino Paulo Filho Soares, Rabelo Samuel Ramos, Junior Fabio Antonio Serra de Lima, Teixeira Vitor Gil Gonçalves, Eisele Roberto Rocha, Eisele Afonso Rocha, de Carvalho João Pedro Serenario Ferreira, Filho Luciano Barroso de Albuquerque, de Medeiros Sara Diógenes Peixoto, Oliveira Leandro Freitas, Claudino Dos Santos Julio Cesar, Júnior Euldes Mendes

机构信息

Christus University Center, Unichristus, Fortaleza, Ceará, Brazil.

Federal University of Piaui, Teresina, Brazil.

出版信息

Radiol Case Rep. 2022 Nov;17(11):4123-4127. doi: 10.1016/j.radcr.2022.06.090. Epub 2022 Sep 2.

Abstract

The Marburg variant of MS is a rare variant that leads to a severe clinical course, with a high rate of mortality or severe residual deficits and unclear pathophysiology. A 20-year-old female patient, presented at the hospital emergency with left inferior limb paresis and visual blurring. The neurologic exam showed complete and proportionate left hemiparesis with pyramidal signs and clonus, loss of proprioception and vibration in lower limbs, tactile, and painful hypoesthesia on the left side. This report describes a rare case of Marburg variant associated with COVID-19 infection.

摘要

多发性硬化的马尔堡变异型是一种罕见变异型,其临床病程严重,死亡率高或有严重的残留缺陷,且病理生理学尚不明确。一名20岁女性患者因左下肢轻瘫和视力模糊到医院急诊。神经系统检查显示左侧完全性、对称性偏瘫,伴有锥体束征和阵挛,下肢本体感觉和振动觉丧失,左侧触觉减退和痛觉减退。本报告描述了一例与新型冠状病毒肺炎感染相关的马尔堡变异型罕见病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eba0/9459429/02fb605e171d/gr1.jpg

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