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腹侧被盖A10区对下丘脑防御反应的抑制作用:多巴胺能介导的可能证据。

Inhibitory effect of the ventral tegmental A10 region on the hypothalamic defence reaction: evidence for a possible dopaminergic mediation.

作者信息

Piazza P V, Ferdico M, Crescimanno G, Benigno A, Amato G

出版信息

Brain Res. 1987 Jun 16;413(2):356-9. doi: 10.1016/0006-8993(87)91028-6.

Abstract

The influence of A10 region neurons of the ventral tegmental area (VTA) on the defence reaction evoked by stimulation of the ventromedial hypothalamic nucleus (VMH) was studied in the cat. The latency of the hissing in the defence reaction increased when the VTA was stimulated both ipsi- and contralaterally. A sulpiride (50mg/kg i.p.) injection totally abolished the VTA-provoked increase of the hissing latency without affecting the basal response.

摘要

在猫身上研究了腹侧被盖区(VTA)A10区神经元对刺激腹内侧下丘脑核(VMH)诱发的防御反应的影响。当同侧和对侧刺激VTA时,防御反应中嘶嘶声的潜伏期增加。注射舒必利(50mg/kg,腹腔注射)完全消除了VTA引起的嘶嘶声潜伏期增加,而不影响基础反应。

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