Mena-Moreno Teresa, Munguía Lucero, Granero Rosario, Lucas Ignacio, Sánchez-Gómez Almudena, Cámara Ana, Compta Yaroslau, Valldeoriola Francesc, Fernandez-Aranda Fernando, Sauvaget Anne, Menchón José M, Jiménez-Murcia Susana
Department of Psychiatry, Bellvitge University Hospital, Hospitalet de Llobregat, Spain.
Centro de Investigación Biomédica en Red-Fisiopatología de la Obesidad y la Nutrición, Instituto de Salud Carlos III, Madrid, Spain.
JMIR Serious Games. 2022 Sep 9;10(3):e33858. doi: 10.2196/33858.
Impulse control disorders (ICDs) are commonly developed among patients who take dopamine agonist drugs as a treatment for Parkinson disease (PD). Gambling disorder and hypersexuality are more frequent in male patients with PD, with a prevalence over 4% in dopamine agonists users. Although impulsive-compulsive behaviors are related to antiparkinsonian medication, and even though ICD symptomatology, such as hypersexuality, often subsides when the dopaminergic dose is reduced, sometimes ICD persists in spite of drug adjustment. Consequently, a multidisciplinary approach should be considered to address these comorbidities and to explore new forms of complementary interventions, such as serious games or therapies adapted to PD.
The aim of this study is to present the case of a patient with ICD (ie, hypersexuality) triggered by dopaminergic medication for PD. A combined intervention was carried out using cognitive behavioral therapy (CBT) for ICD adapted to PD, plus an intervention using a serious game-e-Estesia-whose objective is to improve emotion regulation and impulsivity. The aim of the combination of these interventions was to reduce the harm of the disease.
After 20 CBT sessions, the patient received the e-Estesia intervention over 15 sessions. Repeated measures, before and after the combined intervention, were administered to assess emotion regulation, general psychopathology, and emotional distress and impulsivity.
After the intervention with CBT techniques and e-Estesia, the patient presented fewer difficulties to regulate emotion, less emotional distress, and lower levels of impulsivity in comparison to before the treatment. Moreover, the frequency and severity of the relapses also decreased.
The combined intervention-CBT and a serious game-showed positive results in terms of treatment outcomes.
冲动控制障碍(ICD)常见于服用多巴胺激动剂药物治疗帕金森病(PD)的患者中。赌博障碍和性欲亢进在男性PD患者中更为常见,在多巴胺激动剂使用者中的患病率超过4%。尽管冲动强迫行为与抗帕金森药物有关,且尽管ICD症状,如性欲亢进,在多巴胺能剂量降低时往往会消退,但有时即使调整药物,ICD仍会持续存在。因此,应考虑采用多学科方法来处理这些合并症,并探索新的补充干预形式,如严肃游戏或适用于PD的疗法。
本研究旨在介绍一例因PD的多巴胺能药物引发ICD(即性欲亢进)的患者案例。采用了针对适用于PD的ICD的认知行为疗法(CBT),并结合使用一款严肃游戏——电子Estesia进行干预,其目的是改善情绪调节和冲动性。这些干预措施相结合的目的是减少疾病的危害。
在进行20次CBT治疗后,患者接受了15次电子Estesia干预。在联合干预前后进行重复测量,以评估情绪调节、一般精神病理学、情绪困扰和冲动性。
与治疗前相比,在采用CBT技术和电子Estesia进行干预后,患者在情绪调节方面遇到的困难减少,情绪困扰减轻,冲动性水平降低。此外,复发的频率和严重程度也有所下降。
CBT与严肃游戏相结合的联合干预在治疗效果方面显示出积极的结果。