独立式电阻抗断层成像术可预测肺量计指标并实现区域性肺部评估。
Standalone electrical impedance tomography predicts spirometry indicators and enables regional lung assessment.
出版信息
Annu Int Conf IEEE Eng Med Biol Soc. 2022 Jul;2022:3277-3280. doi: 10.1109/EMBC48229.2022.9871104.
Electrical impedance tomography (EIT) is a bio-medical imaging modality that has several clinical applications namely for human lungs. Yet, its relationship with gold standard lung diagnostic tools including spirometry is not available. In this study, simultaneous EIT and spirometry measurements were collected for 14 healthy subjects who performed forced breathing paradigms of different efforts simulating a wide range of spirometry indicators. It is demonstrated that EIT can predict standard spirometry indicators over a wide dynamic range, with a potential sensitivity and specificity of 98% and 100%, respectively, in detecting obstructive patterns. It is also shown that EIT can provide a regional mapping of the spirometry indicator which are shown to be consistent with their corresponding global indicators. Overall, EIT can predict spirometry indicators and can assess regional lung health through parametric mapping. Clinical Relevance- This study shows that EIT can infer standard spirometry indicators and potentially assess regional lung health. Therefore, EIT can be used for screening, diagnosis, and monitoring of obstructive and resistive lung diseases.
电阻抗断层成像（EIT）是一种生物医学成像模式，在临床上有多种应用，例如用于人类肺部。然而，它与包括肺活量计在内的金标准肺诊断工具的关系尚不清楚。在这项研究中，对 14 名健康受试者同时进行了 EIT 和肺活量计测量，这些受试者进行了不同努力的强制呼吸范式，模拟了广泛的肺活量计指标。结果表明，EIT 可以在很宽的动态范围内预测标准肺活量计指标，在检测阻塞模式时，灵敏度和特异性分别为 98%和 100%。还表明，EIT 可以提供肺活量计指标的区域映射，这些指标与相应的全局指标一致。总体而言，EIT 可以通过参数映射预测肺活量计指标并评估区域肺健康。临床相关性- 这项研究表明，EIT 可以推断标准肺活量计指标，并可能评估区域肺健康。因此，EIT 可用于筛查、诊断和监测阻塞性和阻力性肺疾病。
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