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预防性 B-Lynch 缝线在产后出血高危患者中的效果。

Effectiveness of preventive B-Lynch sutures in patients at a high risk of postpartum hemorrhage.

机构信息

Department of Fetal - Maternal Medicine, Obstetrics, Gifu Prefectural General Medical Center, Gifu, Japan.

出版信息

J Obstet Gynaecol Res. 2022 Dec;48(12):3111-3118. doi: 10.1111/jog.15415. Epub 2022 Sep 11.

Abstract

AIM

We aimed to evaluate the clinical outcomes and adverse events of preventive B-Lynch suture performed during cesarean section in patients at a high risk of postpartum hemorrhage.

METHODS

This retrospective observational study included patients who underwent a cesarean section and the B-Lynch suture at a tertiary perinatal medical center between January 2019 and May 2021. The B-Lynch sutures were placed preventively before excessive blood loss occurred in patients with uterine atony, placental position abnormality (placenta previa and low-lying placenta), placenta accreta, thrombocytopenia, coagulopathy, and other risk factors of bleeding. Partial compression sutures for bleeding points and vaginal gauze packing were placed if required.

RESULTS

The B-Lynch suture was performed in 38 patients, and hysterectomy was avoided in all patients. Only one patient required intrauterine balloon tamponade as an additional treatment 5 days after the cesarean section. No apparent postoperative bleeding occurred within 2 h after the cesarean section in 35 patients (92%), and blood transfusion was avoided in 14 patients (37%). Thirty-three adverse events occurred in 23 patients; these included an inflammatory response, hematomas, retained products of conception, and ileus in one, two, and two patients, respectively. In most cases, the events were not severe and were unrelated to the procedure. In one patient, a second-look operation was performed and no complications were observed in the uterus and abdominal cavity.

CONCLUSIONS

Preventive B-Lynch suture seemed effective and safe after a short-term observation. When excessive bleeding is expected during a cesarean section, an early introduction of this procedure is recommended.

摘要

目的

评估剖宫产术中预防性 B-Lynch 缝合术在产后出血高危患者中的临床结局和不良事件。

方法

本回顾性观察性研究纳入了 2019 年 1 月至 2021 年 5 月在一家三级围产医学中心行剖宫产术和 B-Lynch 缝合术的患者。在发生宫缩乏力、胎盘位置异常(前置胎盘和低置胎盘)、胎盘植入、血小板减少症、凝血功能障碍和其他出血危险因素之前,对有出血风险的患者预防性放置 B-Lynch 缝线。如果需要,放置压迫缝合止血和阴道填塞纱布。

结果

38 例患者行 B-Lynch 缝合术,所有患者均避免了子宫切除术。仅 1 例患者在剖宫产术后 5 天因额外出血接受了宫内球囊填塞治疗。35 例(92%)患者在剖宫产术后 2 小时内无明显术后出血,14 例(37%)患者避免了输血。23 例患者发生 33 例不良事件;分别有 1、2、2 例患者出现炎症反应、血肿、妊娠物残留和肠梗阻。大多数情况下,这些事件并不严重,且与手术无关。1 例患者行二次探查手术,子宫和腹腔未见并发症。

结论

短期观察结果显示预防性 B-Lynch 缝合术是有效且安全的。当预计剖宫产术中会发生大量出血时,建议尽早采用该术式。

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