与小儿 1 型糖尿病相关的传染病：叙述性综述。
Infectious diseases associated with pediatric type 1 diabetes mellitus: A narrative review.
机构信息
Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy.
Neuro-oncology Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
出版信息
Front Endocrinol (Lausanne). 2022 Aug 24;13:966344. doi: 10.3389/fendo.2022.966344. eCollection 2022.
Diabetes mellitus (DM) has been frequently associated with an impaired immune response against infectious agents, making affected patients at risk for more severe disease and sometimes causing worse outcomes. The recent COVID-19 pandemic has seriously affected patients with both diabetes, in particular those carrying comorbidities or with poor glycemic control. As regards pediatric diabetes mellitus, the availability of more accurate and technological tools for glycemic management and the improved markers of metabolic control might mitigate the negative impact of infections. Notably, good metabolic control of diabetes since its diagnosis reduces not only the risk of microangiopathic complications but also of impaired immune response to infectious diseases. Therefore, vaccinations are strongly recommended. Our paper aims to provide the most updated evidence regarding infectious diseases in type 1 pediatric DM.
糖尿病（DM）常与针对感染因子的免疫应答受损相关，使受影响的患者面临更严重疾病的风险，有时还会导致更差的结局。最近的 COVID-19 大流行严重影响了糖尿病患者，尤其是那些合并症或血糖控制不佳的患者。对于儿童糖尿病，血糖管理的更准确和技术工具的可用性以及代谢控制的改善标志物可能会减轻感染的负面影响。值得注意的是，自诊断以来糖尿病的良好代谢控制不仅降低了微血管并发症的风险，还降低了对传染病的免疫应答受损的风险。因此，强烈建议接种疫苗。我们的论文旨在提供有关 1 型儿科 DM 中传染病的最新证据。
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