与小儿 1 型糖尿病相关的传染病：叙述性综述。
Infectious diseases associated with pediatric type 1 diabetes mellitus: A narrative review.
机构信息
Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy.
Neuro-oncology Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
出版信息
Front Endocrinol (Lausanne). 2022 Aug 24;13:966344. doi: 10.3389/fendo.2022.966344. eCollection 2022.
Abstract
Diabetes mellitus (DM) has been frequently associated with an impaired immune response against infectious agents, making affected patients at risk for more severe disease and sometimes causing worse outcomes. The recent COVID-19 pandemic has seriously affected patients with both diabetes, in particular those carrying comorbidities or with poor glycemic control. As regards pediatric diabetes mellitus, the availability of more accurate and technological tools for glycemic management and the improved markers of metabolic control might mitigate the negative impact of infections. Notably, good metabolic control of diabetes since its diagnosis reduces not only the risk of microangiopathic complications but also of impaired immune response to infectious diseases. Therefore, vaccinations are strongly recommended. Our paper aims to provide the most updated evidence regarding infectious diseases in type 1 pediatric DM.
摘要
糖尿病（DM）常与针对感染因子的免疫应答受损相关，使受影响的患者面临更严重疾病的风险，有时还会导致更差的结局。最近的 COVID-19 大流行严重影响了糖尿病患者，尤其是那些合并症或血糖控制不佳的患者。对于儿童糖尿病，血糖管理的更准确和技术工具的可用性以及代谢控制的改善标志物可能会减轻感染的负面影响。值得注意的是，自诊断以来糖尿病的良好代谢控制不仅降低了微血管并发症的风险，还降低了对传染病的免疫应答受损的风险。因此，强烈建议接种疫苗。我们的论文旨在提供有关 1 型儿科 DM 中传染病的最新证据。
相似文献
1
Infectious diseases associated with pediatric type 1 diabetes mellitus: A narrative review.与小儿 1 型糖尿病相关的传染病：叙述性综述。
Front Endocrinol (Lausanne). 2022 Aug 24;13:966344. doi: 10.3389/fendo.2022.966344. eCollection 2022.
2
Diabetic ketoacidosis in pediatric patients with type 1- and type 2 diabetes during the COVID-19 pandemic.COVID-19 大流行期间 1 型和 2 型糖尿病患儿的糖尿病酮症酸中毒。
Metabolism. 2021 Sep;122:154842. doi: 10.1016/j.metabol.2021.154842. Epub 2021 Jul 30.
3
Diabetes and COVID19: a bidirectional relationship.糖尿病与 COVID-19：双向关系。
Nutr Diabetes. 2021 Jun 23;11(1):21. doi: 10.1038/s41387-021-00163-2.
4
The Effects of COVID-19 Pandemic and Lockdown on Pediatric Nutritional and Metabolic Diseases: A Narrative Review.新冠疫情和封控对儿科营养和代谢性疾病的影响：一项叙述性综述。
Nutrients. 2022 Dec 24;15(1):88. doi: 10.3390/nu15010088.
5
Teleconsultation for pediatric patients with type 1 diabetes mellitus during the COVID-19 pandemic: experience of a university hospital in Brazil.COVID-19 大流行期间 1 型糖尿病儿科患者的远程会诊：巴西一所大学医院的经验。
J Pediatr (Rio J). 2022 Nov-Dec;98(6):587-589. doi: 10.1016/j.jped.2022.02.001. Epub 2022 Mar 1.
6
Outcomes of hyperglycemia in patients with and without diabetes hospitalized for infectious diseases.感染性疾病住院患者中合并与不合并糖尿病患者的高血糖结局。
Diabetes Metab Res Rev. 2018 Oct;34(7):e3027. doi: 10.1002/dmrr.3027. Epub 2018 Jun 14.
7
Clinical and laboratory profile and outcomes of hospitalized COVID-19 patients with type 2 diabetes mellitus in Ghana - A single-center study.加纳住院 COVID-19 合并 2 型糖尿病患者的临床和实验室特征及转归：一项单中心研究。
Endocrinol Diabetes Metab. 2023 Jan;6(1):e391. doi: 10.1002/edm2.391. Epub 2022 Nov 25.
8
Pediatric diabetes mellitus hospitalizations and COVID-19 pandemic response measures.儿科糖尿病住院情况及新冠疫情应对措施
Diabetes Res Clin Pract. 2024 Jan;207:111060. doi: 10.1016/j.diabres.2023.111060. Epub 2023 Dec 16.
9
Glycemic Dysregulation, Inflammation and Disease Outcomes in Patients Hospitalized with COVID-19: Beyond Diabetes and Obesity.血糖调节异常、炎症与 COVID-19 住院患者的疾病转归：超越糖尿病和肥胖。
Viruses. 2023 Jun 28;15(7):1468. doi: 10.3390/v15071468.
10
Assessment of risk, severity, mortality, glycemic control and antidiabetic agents in patients with diabetes and COVID-19: A narrative review.评估糖尿病合并 COVID-19 患者的风险、严重程度、死亡率、血糖控制和抗糖尿病药物：叙述性综述。
Diabetes Res Clin Pract. 2020 Jul;165:108266. doi: 10.1016/j.diabres.2020.108266. Epub 2020 Jun 11.
引用本文的文献
1
Diabetes Insipidus Complicating Diabetes Mellitus Type 1: A Pituitary Abscess Diagnosis.1型糖尿病并发尿崩症：垂体脓肿的诊断
JCEM Case Rep. 2024 Jun 3;2(6):luae057. doi: 10.1210/jcemcr/luae057. eCollection 2024 Jun.
2
Endocrinological Involvement in Children and Adolescents Affected by COVID-19: A Narrative Review.新型冠状病毒肺炎（COVID-19）对儿童和青少年内分泌系统的影响：一篇叙述性综述
J Clin Med. 2023 Aug 11;12(16):5248. doi: 10.3390/jcm12165248.
3
Monovalent SARS-CoV-2 mRNA Vaccine Does not Boost Omicron-Specific Immune Response in Diabetic and Control Pediatric Patients.单价 SARS-CoV-2 mRNA 疫苗不会增强糖尿病和对照儿科患者的奥密克戎特异性免疫应答。
J Infect Dis. 2024 Apr 12;229(4):1059-1067. doi: 10.1093/infdis/jiad366.
4
Two putative glutamate decarboxylases of Streptococcus pneumoniae as possible antigens for the production of anti-GAD65 antibodies leading to type 1 diabetes mellitus.肺炎链球菌的两种假定谷氨酸脱羧酶作为产生抗 GAD65 抗体的可能抗原，导致 1 型糖尿病。
Int Microbiol. 2023 Aug;26(3):675-690. doi: 10.1007/s10123-023-00364-y. Epub 2023 May 8.
5
Causal relationship between type 1 diabetes mellitus and six high-frequency infectious diseases: A two-sample mendelian randomization study.1 型糖尿病与六种高发传染病之间的因果关系：一项两样本孟德尔随机化研究。
Front Endocrinol (Lausanne). 2023 Mar 31;14:1135726. doi: 10.3389/fendo.2023.1135726. eCollection 2023.
本文引用的文献
1
Impact of diabetes on COVID-19 mortality and hospital outcomes from a global perspective: An umbrella systematic review and meta-analysis.从全球视角看糖尿病对 COVID-19 死亡率和医院转归的影响：伞式系统评价和荟萃分析。
Endocrinol Diabetes Metab. 2022 May;5(3):e00338. doi: 10.1002/edm2.338. Epub 2022 Apr 20.
2
Emphysematous cystitis with bilateral pyelonephritis in a pediatric patient with COVID-19.儿童 COVID-19 患者并发气肿性膀胱炎伴双侧肾盂肾炎。
BMJ Case Rep. 2022 Feb 3;15(2):e245779. doi: 10.1136/bcr-2021-245779.
3
Rates and associates of influenza and pneumococcus vaccination in diabetes mellitus: A nationwide cross-sectional study (TEMD vaccination study).糖尿病患者中流感和肺炎球菌疫苗接种率及其相关因素：一项全国性横断面研究（TEMD疫苗接种研究）
World J Diabetes. 2021 Dec 15;12(12):2107-2118. doi: 10.4239/wjd.v12.i12.2107.
4
Incidence of Type 1 Diabetes in Children and Adolescents During the COVID-19 Pandemic in Germany: Results From the DPV Registry.德国 COVID-19 大流行期间儿童和青少年 1 型糖尿病的发病率：来自 DPV 登记处的结果。
Diabetes Care. 2022 Aug 1;45(8):1762-1771. doi: 10.2337/dc21-0969.
5
Risk for Newly Diagnosed Diabetes >30 Days After SARS-CoV-2 Infection Among Persons Aged <18 Years - United States, March 1, 2020-June 28, 2021.2020 年 3 月 1 日至 2021 年 6 月 28 日期间，年龄<18 岁的 SARS-CoV-2 感染者在新冠病毒感染后 30 天以上新发糖尿病的风险。
MMWR Morb Mortal Wkly Rep. 2022 Jan 14;71(2):59-65. doi: 10.15585/mmwr.mm7102e2.
6
Risk Factors for Severe COVID-19 in Children.儿童重症 COVID-19 的危险因素。
Pediatrics. 2022 Jan 1;149(1). doi: 10.1542/peds.2021-053418. Epub 2021 Dec 22.
7
Increased Incidence of Type 1 Diabetes during the COVID-19 Pandemic in Romanian Children.罗马尼亚儿童在 COVID-19 大流行期间 1 型糖尿病发病率上升。
Medicina (Kaunas). 2021 Sep 16;57(9):973. doi: 10.3390/medicina57090973.
8
Emphysematous Pyelonephritis and Emphysematous Cholecystitis: A Result of Uncontrolled Type 2 Diabetes.气肿性肾盂肾炎和气肿性胆囊炎：2型糖尿病控制不佳的结果
Ochsner J. 2021 Fall;21(3):316-318. doi: 10.31486/toj.20.0126.
9
Large fibre, small fibre and autonomic neuropathy in adolescents with type 1 diabetes: A systematic review.青少年 1 型糖尿病中大纤维、小纤维和自主神经病变：系统评价。
J Diabetes Complications. 2021 Nov;35(11):108027. doi: 10.1016/j.jdiacomp.2021.108027. Epub 2021 Aug 18.
10
Trends in Prevalence of Type 1 and Type 2 Diabetes in Children and Adolescents in the US, 2001-2017.美国儿童和青少年 1 型和 2 型糖尿病患病率趋势，2001-2017 年。
JAMA. 2021 Aug 24;326(8):717-727. doi: 10.1001/jama.2021.11165.
Zotero 插件