Synthesis of Enamines, Aldehydes, and Nitriles from CO: Scope of the One-Pot Strategy via Formamides.
作者信息
Nakaoka Koichi, Guo Chao, Saiki Yuta, Furukawa Shin, Ema Tadashi
机构信息
Division of Applied Chemistry, Graduate School of Natural Science and Technology, Okayama University, Okayama 700-8530, Japan.
出版信息
J Org Chem. 2023 Nov 3;88(21):15444-15451. doi: 10.1021/acs.joc.2c01666. Epub 2022 Sep 13.
PMID:36099541
Abstract
Tetrabutylammonium acetate (TBAA) and Cu(OAc) worked as a binary catalytic system for the solvent-free -formylation of amines with CO and PhSiH. This catalysis making C-H and C-N bonds with CO was coupled with the C-C bond-forming reactions to achieve the one-pot synthesis of enamines, aldehydes, and nitriles. The X-ray crystal structure of a Cu(OAc)-TBAA complex was also revealed.
摘要
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