安慰剂与溴隐亭治疗血催乳素正常性闭经患者的比较

Comparison of placebo and bromocriptine in the treatment of patients with normoprolactinaemic amenorrhoea.

作者信息

Crosignani P G, Reschini E, Lombroso G C, Arosio M, Peracchi M

出版信息

Br J Obstet Gynaecol. 1978 Oct;85(10):773-5. doi: 10.1111/j.1471-0528.1978.tb15601.x.

DOI:10.1111/j.1471-0528.1978.tb15601.x

Abstract

Fourteen women with normoprolactinaemic amenorrhoea were treated with bromocriptine (2.5 mg twice daily) for a period ranging from 4 to 17 weeks, while a matched group fo 19 amenorrhoeic women were treated with a placebo (one tablet twice daily) for 4 to 12 weeks. About half of the patients in both groups had at least one episode of vaginal bleeding during treatment. There was no clear difference in the menstrual and ovulatory pattern between placebo and bromocriptine groups.

摘要

14名患有正常泌乳素血症性闭经的女性接受了溴隐亭治疗（每日2次，每次2.5毫克），疗程为4至17周，而另一组19名闭经女性则接受安慰剂治疗（每日2次，每次1片），疗程为4至12周。两组中约一半的患者在治疗期间至少有一次阴道出血。安慰剂组和溴隐亭组在月经和排卵模式上没有明显差异。