Department of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, California, USA.
Oregon Health & Science University-Portland State University School of Public Health, Portland, Oregon, USA.
Clin Infect Dis. 2023 Jan 13;76(2):338-341. doi: 10.1093/cid/ciac788.
Among 1038 participants with pulmonary Mycobacterium avium complex and 120 with Mycobacterium abscessus enrolled in the US Bronchiectasis and NTM Research Registry, less than half received antibiotic therapy in the 24 months before registry enrollment, of which less than half were guideline based. Adverse effects occurred in 21% of therapy recipients, of whom 33% discontinued therapy.
在美国支气管扩张症和非结核分枝杆菌研究注册中心,1038 名患有肺部鸟分枝杆菌复合体和 120 名患有脓肿分枝杆菌的参与者中,不到一半的人在注册前 24 个月接受了抗生素治疗,其中不到一半的人是基于指南的。治疗的不良反应发生率为 21%,其中 33%的人停止了治疗。