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美国支气管扩张症和非结核分枝杆菌(NTM)登记处中治疗非结核分枝杆菌(NTM)肺部感染:治疗模式、不良事件以及对美国胸科学会/传染病学会治疗指南的遵循情况。

Treatment of Nontuberculous Mycobacterial (NTM) Pulmonary Infection in the US Bronchiectasis and NTM Registry: Treatment Patterns, Adverse Events, and Adherence to American Thoracic Society/Infectious Disease Society of America Treatment Guidelines.

机构信息

Department of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, California, USA.

Oregon Health & Science University-Portland State University School of Public Health, Portland, Oregon, USA.

出版信息

Clin Infect Dis. 2023 Jan 13;76(2):338-341. doi: 10.1093/cid/ciac788.

Abstract

Among 1038 participants with pulmonary Mycobacterium avium complex and 120 with Mycobacterium abscessus enrolled in the US Bronchiectasis and NTM Research Registry, less than half received antibiotic therapy in the 24 months before registry enrollment, of which less than half were guideline based. Adverse effects occurred in 21% of therapy recipients, of whom 33% discontinued therapy.

摘要

在美国支气管扩张症和非结核分枝杆菌研究注册中心,1038 名患有肺部鸟分枝杆菌复合体和 120 名患有脓肿分枝杆菌的参与者中,不到一半的人在注册前 24 个月接受了抗生素治疗,其中不到一半的人是基于指南的。治疗的不良反应发生率为 21%,其中 33%的人停止了治疗。

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