严重急性呼吸综合征冠状病毒2型感染导致二尖瓣生物瓣大量血栓形成

Massive Thrombosis of Mitral Bioprosthesis Due to SARS-CoV-2 Infection.

作者信息

Librera Mariateresa, Paolillo Stefania, Carlomagno Guido, Santise Gianluca, Mariniello Antonio, Nardella Saverio, Briguori Carlo, Maselli Daniele

机构信息

Cardiac Multi-Imaging Unit, Mediterranea Cardiocentro, Via Orazio 2, 80122 Naples, Italy.

Department of Advanced Biomedical Sciences, Federico II University of Naples, Via Pansini 5, 80131 Naples, Italy.

出版信息

J Clin Med. 2022 Sep 7;11(18):5277. doi: 10.3390/jcm11185277.

DOI:10.3390/jcm11185277

PMID:36142921

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9505639/

Abstract

Thromboembolic events have been reported as frequent and fearsome complications in patients affected by SARS-CoV-2 infection. Patients undergoing cardiac valve replacement exhibit an increased risk of valve thrombosis, even with prosthetic biological valves, and especially in the first period after surgery. The management of these patients is challenging and requires prompt interventions. We report the case of a young woman infected by SARS-CoV-2 three months after double cardiac valve replacement that developed a massive prosthetic biological valve thrombosis despite optimal anticoagulant therapy.

摘要

血栓栓塞事件已被报道为感染SARS-CoV-2的患者中常见且可怕的并发症。接受心脏瓣膜置换术的患者出现瓣膜血栓形成的风险增加，即使使用人工生物瓣膜也是如此，尤其是在术后的第一个时期。这些患者的管理具有挑战性，需要及时干预。我们报告了一名年轻女性的病例，她在进行双心脏瓣膜置换术后三个月感染了SARS-CoV-2，尽管接受了最佳的抗凝治疗，但仍发生了大规模人工生物瓣膜血栓形成。