East of Scotland Deanery, Scotland, UK.
NHS Tayside, Dundee, Scotland, UK.
J R Coll Physicians Edinb. 2022 Mar;52(1):42-45. doi: 10.1177/14782715221088972.
Hyperammonaemia is a life-threatening condition with numerous aetiologies and a variable presentation. It is increasingly associated with bariatric weight-loss procedures and significant mortality despite treatment. Symptoms often occur long after surgery and at times in association with other trigger illnesses. Patients can present to general medicine, general practice and intensive care as well as surgical and anaesthetic teams. We present the case of a male patient who underwent a sleeve gastrectomy with subsequent weight loss and suffered from hyperammonaemic encephalopathy on multiple occasions. His delayed postoperative complication was likely to be multifactorial in nature, and this is outlined in the case. We discuss presentation, investigation, management and patient outcomes.
高血氨症是一种危及生命的病症,有多种病因和多变的表现。尽管进行了治疗,它还是与减肥手术和高死亡率相关。症状常常在手术后很久才出现,有时还与其他诱发疾病相关。患者可以到内科、全科医生和重症监护病房就诊,也可以到外科和麻醉科就诊。我们报告了一例男性患者,他接受了袖状胃切除术,随后体重减轻,并多次出现高氨血症性脑病。他的术后迟发性并发症很可能是多因素的,这在病例中进行了阐述。我们讨论了其表现、检查、治疗和患者结局。