脑电图背景频率与非重症监护病房住院的新冠肺炎患者的放电结果相关。
EEG background frequency is associated with discharge outcomes in non-ICU hospitalized patients with COVID-19.
作者信息
Seibert Kaitlin M, Lee Wonhee, Eid Alexandra, Espinal Amy E, Klein Sara A, Abumurad Sumayyah K, Tao James X, Issa Naoum P
机构信息
Department of Neurology, University of Chicago, Chicago, IL, United States.
出版信息
Front Neurol. 2022 Aug 29;13:941903. doi: 10.3389/fneur.2022.941903. eCollection 2022.
OBJECTIVE
To assess risk factors for encephalopathy in non-ICU hospitalized patients with COVID-19 and the effect of encephalopathy on short-term outcomes.
METHODS
We collected clinical and electrophysiological characteristics of fifty patients with COVID-19 infection admitted to a ward service and who had an electroencephalogram (EEG) performed. Associations with short-term outcomes including hospital length of stay and discharge disposition were determined from univariate and multivariate statistical analysis.
RESULTS
Clinical delirium was associated with encephalopathy on EEG, cefepime use was associated with increased length of stay, and of all factors analyzed, background frequency on EEG alone was correlated with discharge disposition.
CONCLUSION
Encephalopathy is one of the major determinants of short-term outcomes in hospitalized non-ICU patients with COVID-19.
目的
评估非重症监护病房（ICU）住院的新型冠状病毒肺炎（COVID-19）患者发生脑病的危险因素以及脑病对短期预后的影响。
方法
我们收集了50例入住病房且进行了脑电图（EEG）检查的COVID-19感染患者的临床和电生理特征。通过单因素和多因素统计分析确定与短期预后（包括住院时间和出院情况）的相关性。
结果
临床谵妄与EEG显示的脑病相关，使用头孢吡肟与住院时间延长相关，在所有分析的因素中，仅EEG的背景频率与出院情况相关。
结论
脑病是住院的非ICU COVID-19患者短期预后的主要决定因素之一。
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