Gupta Ashutosh, Nair Rajeev, Singh Shalendra, Khanna Hitesh, Bal Amresh, Patrikar Seema
Graded Specialist (Anaesthesia), Military Hospital Ranikhet, Almora, India.
Commandant 150 General Hospital, C/o 56 APO, India.
Med J Armed Forces India. 2022 Sep;78(Suppl 1):S111-S115. doi: 10.1016/j.mjafi.2022.01.004. Epub 2022 Apr 2.
Millions of patients admitted globally in health care setups require insertion of peripheral intravascular catheter for intravenous drugs or fluid administration. However, if proper precautions are not followed during insertion, it results in significant morbidity. This study was designed to study the efficacy and safety of recommended Centre for Disease Control and Prevention (CDC) guidelines for peripheral intravascular catheter insertion practice and its comparison with a standard insertion protocol being followed and their outcome.
Patients were randomized and catheter was inserted as recommended by CDC guideline (Group 1, = 100) or followed standard defined steps during insertion (Group 2, = 100).
Almost double the patients had occurrence of thrombophlebitis in Group 1 ( = 0.02). No difference observed between catheter needle size and infection rates (p = 0.3). Infection rate increased significantly if second attempt is taken for insertion. The time required to insert catheter following CDC recommended protocol is less than as by standard surgical complete asepsis cleaning protocol (86.03 vs 109.40 s) (p = 0.001). Study also observed that insertion at wrist joint leads to higher incidence of thrombophlebitis. During 0-24 h, 6% (12) insertions turned positive followed by a dip during 25-48 h, 2% (5) insertions. 80% (159) insertions did not develop thrombophlebitis at the end of 72 h.
It is thus amply demonstrated that meticulous adherence to insertion procedure with asepsis plays an important role in decreasing intravascular catheter associated morbidity. Other parameters like needle gauge, sites of insertion, have little bearing. The time required in following standard aseptic technique is significantly more but keeping in view the benefit to the patient it is highly recommended.
全球数百万在医疗机构住院的患者需要插入外周血管导管以进行静脉药物或液体输注。然而,如果在插入过程中未遵循适当的预防措施,会导致严重的发病情况。本研究旨在探讨美国疾病控制与预防中心(CDC)推荐的外周血管导管插入操作指南的有效性和安全性,并将其与正在遵循的标准插入方案进行比较及其结果。
将患者随机分组,并按照CDC指南推荐插入导管(第1组,n = 100)或在插入过程中遵循标准定义步骤(第2组,n = 100)。
第1组发生血栓性静脉炎的患者几乎是第2组的两倍(P = 0.02)。导管针尺寸与感染率之间未观察到差异(P = 0.3)。如果进行第二次插入尝试,感染率会显著增加。按照CDC推荐方案插入导管所需的时间比标准外科完全无菌清洁方案所需时间少(86.03秒对109.40秒)(P = 0.001)。研究还观察到在腕关节处插入会导致血栓性静脉炎的发病率更高。在0 - 24小时内,6%(12例)插入部位呈阳性,随后在25 - 48小时内有所下降,为2%(5例)插入部位。在72小时结束时,80%(159例)插入部位未发生血栓性静脉炎。
因此充分证明,严格遵守无菌插入程序在降低血管内导管相关发病情况方面起着重要作用。其他参数如针规、插入部位影响较小。遵循标准无菌技术所需时间明显更长,但鉴于对患者的益处,强烈推荐使用。