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阿托品滴眼液联合基于虚拟现实的双眼视觉功能平衡训练对青少年近视防控的效果

Effect of Atropine Eye Drops Combined with VR-Based Binocular Visual Function Balance Training for Prevention and Control of Juvenile Myopia.

作者信息

Shi Yuping

机构信息

Chengdu Aier Eye Hospital, Chengdu 610041, Sichuan, China.

出版信息

Evid Based Complement Alternat Med. 2022 Sep 13;2022:4159996. doi: 10.1155/2022/4159996. eCollection 2022.

DOI:10.1155/2022/4159996
PMID:36147642
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9489366/
Abstract

PURPOSE

This study mainly analyzes the efficacy of 0.01% atropine eye drops (low-dose atropine (LDA)) combined with virtual reality (VR)-based binocular visual function (BVF) balance training in the prevention and control of juvenile myopia.

METHODS

One hundred and thirty-six juvenile myopia patients admitted between November 2018 to November 2021 were selected, including 76 cases (research group) receiving LDA + VR-based BVF balance training and 60 cases (control group) treated by LDA intervention alone. Visual acuity (VA; naked vision), ocular parameters (pupil diameter (PD), axial length (AXL), and diopter), intraocular pressure (IOP), accommodation facility, clinical efficacy, and incidence of adverse reactions were observed, compared, and analyzed in both groups.

RESULTS

After analysis, it was found that the research group showed significantly higher naked vision and PD while statistically lower after intervention than the corresponding preinterventional parameters than the control group. While AXL showed no statistical difference between the groups and within groups. The IOP also differed insignificantly between groups, but the post-treatment accommodation facility was better in the research group compared with the baseline (before treatment) and control group. In terms of curative effects, an obviously higher total effective rate was determined in the research group. In addition, the two groups showed no significant difference in the incidence of adverse reactions.

CONCLUSIONS

LDA + VR-based BVF balance training deserves clinical popularization, as it can prevent and control myopia among teenagers, with better adjusting effects on eye function and certain safety.

摘要

目的

本研究主要分析0.01%阿托品滴眼液(低剂量阿托品(LDA))联合基于虚拟现实(VR)的双眼视觉功能(BVF)平衡训练在青少年近视防控中的疗效。

方法

选取2018年11月至2021年11月收治的136例青少年近视患者,其中76例(研究组)接受LDA联合基于VR的BVF平衡训练,60例(对照组)仅接受LDA干预。观察、比较和分析两组患者的视力(VA;裸眼视力)、眼部参数(瞳孔直径(PD)、眼轴长度(AXL)和屈光度)、眼压(IOP)、调节功能、临床疗效及不良反应发生率。

结果

分析发现,研究组干预后的裸眼视力和PD显著高于对照组,而相应的干预前参数则低于对照组。两组间及组内AXL无统计学差异。两组间眼压也无显著差异,但研究组治疗后的调节功能较基线(治疗前)和对照组更好。在疗效方面,研究组的总有效率明显更高。此外,两组不良反应发生率无显著差异。

结论

LDA联合基于VR的BVF平衡训练值得临床推广,因为它可以防控青少年近视,对眼功能有更好的调节作用且具有一定安全性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c52/9489366/38af6f5a98b1/ECAM2022-4159996.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c52/9489366/c0ba673ab0e6/ECAM2022-4159996.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c52/9489366/aee69bfdb671/ECAM2022-4159996.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c52/9489366/38af6f5a98b1/ECAM2022-4159996.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c52/9489366/c0ba673ab0e6/ECAM2022-4159996.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c52/9489366/aee69bfdb671/ECAM2022-4159996.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c52/9489366/38af6f5a98b1/ECAM2022-4159996.003.jpg