Huang Qilin, Wu Xia, Xia Qin, Xie Zhen, Xiao Hongjun, Sun Yu, Jia Yulin, Yao Dongxiao, Guang Xuan, Cheng Huamao
Department of Otorhinolaryngology, Huazhong University of Science and Technology, Wuhan, China.
Department of Pathology, Huazhong University of Science and Technology, Wuhan, China.
Ear Nose Throat J. 2025 Jul;104(7):NP450-NP455. doi: 10.1177/01455613221127578. Epub 2022 Sep 23.
Diffuse-type tenosynovial giant cell tumor (D-TSGCT) is a destructive benign tumor-like proliferative disease that occurs in synovial tissue characterized by villous nodular hyperplasia of joints, tendon sheaths, and synovium. D-TSGCT invading the temporal bone originating from the temporomandibular joint (TMJ) is very rare. Here, we report 3 cases of temporal bone D-TSGCT originating from the TMJ. The tumors in the three cases were originating from the TMJ and further invading the middle ear, the carotid foramen or the temporal lobe respectively. The second patient clearly involved the carotid foramen. The third patient clearly affected the temporal lobe. Lesions were completely removed in 3 cases, and all 3 patients were followed up for 30, 20, and 7 months, and none had recurrence. There are very few reports describing such cases. Although this report is not representative of most scenarios, there is still a potential that it provides a relatively reliable surgical idea for similar cases.
弥漫型腱鞘巨细胞瘤(D-TSGCT)是一种具有破坏性的良性肿瘤样增殖性疾病,发生于滑膜组织,其特征为关节、腱鞘和滑膜的绒毛结节性增生。起源于颞下颌关节(TMJ)并侵犯颞骨的D-TSGCT非常罕见。在此,我们报告3例起源于TMJ的颞骨D-TSGCT病例。这3例病例中的肿瘤均起源于TMJ,分别进一步侵犯中耳、颈动脉孔或颞叶。第二例患者明显累及颈动脉孔。第三例患者明显累及颞叶。3例病例均将病变完整切除,所有3例患者分别随访30、20和7个月,均无复发。描述此类病例的报告非常少。尽管本报告不代表大多数情况,但仍有可能为类似病例提供相对可靠的手术思路。