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血清CA19-9和CA125水平显著升高的子宫腺肌病囊肿:一例报告

Uterine adenomyotic cyst with markedly elevated serum CA19‑9 and CA125 levels: A case report.

作者信息

Zheng Lihua, Shan Li, Cai Fengfeng

机构信息

Department of Gynecology and Obstetrics, Northwest Women's and Children's Hospital, Xi'an, Shaanxi 710012, P.R. China.

Department of Breast Surgery, Yangpu Hospital, School of Medicine, Tongji University, Shanghai 200090, P.R. China.

出版信息

Exp Ther Med. 2022 Sep 7;24(5):665. doi: 10.3892/etm.2022.11601. eCollection 2022 Nov.

Abstract

Adenomyotic cysts are small cysts with a diameter of <5 mm, usually containing hemorrhagic material. The present study reported on a patient with a large adenomyotic cyst with abnormally high serum levels of CA19-9 (>1,000 U/ml) and CA125 (642 U/ml) and a complaint of pelvic pain. MRI scans were critical in diagnosing the case. Adhering to the principle of tumor-free implantation, a laparotomy was performed. After the operation, six weeks were required to normalize the serum level of CA19-9 and four weeks for CA125. Elevated tumor markers are frequently observed in malignancies, but the outcome reported in the present case was a benign lesion and the prognosis was favorable. In the present case, it was unusual that CA19-9 was elevated in addition to CA125, as it is commonly reported that only CA125 is elevated in cases of large adenomyotic cyst.

摘要

子宫腺肌病囊肿是直径小于5毫米的小囊肿,通常含有血性物质。本研究报告了一名患有大子宫腺肌病囊肿的患者,其血清CA19-9水平异常升高(>1000 U/ml),CA125水平为642 U/ml,并伴有盆腔疼痛。MRI扫描对该病例的诊断至关重要。遵循无瘤植入原则,进行了剖腹手术。术后,CA19-9血清水平需要六周恢复正常,CA125则需要四周。肿瘤标志物升高在恶性肿瘤中经常可见,但本病例报告的结果是良性病变,预后良好。在本病例中,除CA125升高外CA19-9也升高是不寻常的,因为通常报道大子宫腺肌病囊肿病例中只有CA125升高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fca/9475347/f42a2d0980e2/etm-24-05-11601-g00.jpg

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