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比较综合征型颅缝早闭不同手术方法引起的颅内体积增加。

Comparing the Increased Intracranial Volume From Different Surgical Methods for Syndromic Craniosynostosis.

机构信息

Department of Plastic Surgery, Children Hospital of Fudan University.

Department of Radiology, Children Hospital of Fudan University, ShangHai, China.

出版信息

J Craniofac Surg. 2022;33(8):2529-2533. doi: 10.1097/SCS.0000000000008791. Epub 2022 Sep 29.

Abstract

PURPOSE

Fronto-orbital advancement (FOA) is the traditional surgical method used to increase intracranial volume, but posterior cranial vault distraction osteogenesis (PVDO) has been gaining popularity as an initial treatment option. This study aimed to compare the effects of FOA and PVDO on intracranial volume.

PATIENTS AND METHODS

Sixteen patients with multiple-suture synostosis and severe intracranial volume restriction were treated with FOA or PVDO at Children's Hospital of Fudan University between January 2016 and December 2019. Data on age at surgery, sex, preoperative intracranial volume, and postoperative intracranial volume were collected.

RESULTS

Seven patients underwent FOA and 9 underwent PVDO. All patients underwent surgery for the first time, and the surgeries were performed by the same physician. There was no statistically significant difference in age at surgery or in the intracranial volumes before and after surgery between the 2 groups ( P >0.05). There was a statistically significant difference in the intracranial volume changes between the 2 groups before and after surgery ( P =0.028).

CONCLUSIONS

Posterior cranial vault distraction osteogenesis provided statistically greater intracranial volume expansion than FOA.

摘要

目的

额眶前移术(FOA)是传统的用于增加颅内容积的手术方法,但颅后窝颅骨扩张牵张成骨术(PVDO)作为初始治疗选择越来越受到关注。本研究旨在比较 FOA 和 PVDO 对颅内容积的影响。

患者与方法

复旦大学附属儿科医院于 2016 年 1 月至 2019 年 12 月期间对 16 例矢状缝早闭合并严重颅内容积受限的患者采用 FOA 或 PVDO 进行治疗。收集了手术年龄、性别、术前颅内容积和术后颅内容积等数据。

结果

7 例患者接受 FOA,9 例患者接受 PVDO。所有患者均首次接受手术,且由同一位医师进行手术。两组患者的手术年龄以及手术前后的颅内容积均无统计学差异(P>0.05)。两组患者手术前后的颅内容积变化有统计学差异(P=0.028)。

结论

颅后窝颅骨扩张牵张成骨术在提供颅内容积扩张方面明显优于 FOA。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79dd/9612681/0a21478ec3c5/scs-33-2529-g001.jpg

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