Department of Health and Care Sciences, Faculty of Health Sciences, UiT the Arctic University of Norway, Tromsø, Norway; Department of Clinical Therapeutic Services, University Hospital North Norway, Tromsø, Norway.
Regional Center for Child and Youth Mental Health and Child Welfare, UiT the Arctic University of Norway, Tromsø, Norway.
Early Hum Dev. 2022 Nov;174:105680. doi: 10.1016/j.earlhumdev.2022.105680. Epub 2022 Sep 25.
Interventions involving both the parent and the preterm infant have demonstrated lasting effects on cognitive outcomes, but motor effects are less salient. It remains unclear when to commence early intervention and if dosages have impact on motor outcomes.
To examine the effect on motor performance at 24-months corrected age following a parent-administered intervention performed with infants born preterm in the NICU. Intervention dosing and longitudinal motor performance were also analyzed.
Single-blinded randomized multicenter clinical trial.
153 infants born, gestational age ≤ 32 weeks at birth, were randomized into intervention or control group.
Infant Motor Performance Screening Test, Test of Infant Motor Performance, Peabody Developmental Motor Scales-2.
No significant difference was found between the intervention and the control group assessed with the PDMS-2 at 24-months CA. However, a significant positive association was found between dosing and the Gross Motor and Total Motor PDMS-2 scores. Analysis of longitudinal motor performance showed a decreasing motor performance between 6- and 24-months corrected age in both groups.
There was no difference in motor performance between groups at 24-months corrected age. However, increased intervention dosage was positively associated with improved motor outcome.
涉及父母和早产儿的干预措施已证明对认知结果具有持久影响，但运动效果则不那么明显。目前尚不清楚何时开始早期干预，以及剂量是否对运动结果有影响。
研究在新生儿重症监护病房中对早产儿进行父母参与的干预后，在 24 个月校正年龄时对运动表现的影响。还分析了干预剂量和纵向运动表现。
单盲随机多中心临床试验。
153 名出生时胎龄≤32 周的婴儿被随机分为干预组或对照组。
在 24 个月 CA 时，使用 PDMS-2 评估，干预组和对照组之间没有发现显著差异。然而，剂量与粗大运动和总运动 PDMS-2 评分之间存在显著的正相关。纵向运动表现的分析表明，两组在 6 至 24 个月校正年龄之间的运动表现都有所下降。
在 24 个月校正年龄时，两组之间的运动表现没有差异。然而，干预剂量的增加与运动结果的改善呈正相关。
