Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, USA.
J Affect Disord. 2023 Jan 1;320:196-200. doi: 10.1016/j.jad.2022.09.121. Epub 2022 Sep 30.
Personality traits may confer vulnerability to psychopathology. However, few studies have examined the association between personality traits and obsessive-compulsive disorder (OCD) course. The present study investigates personality traits, OCD symptom severity, and illness duration as a predictor of OCD remission.
166 treatment-seeking adults with OCD, recruited as part of the Brown Longitudinal Obsessive-Compulsive Study, completed the NEO Five-Factor Inventory 3 (NEO-FFI) and were in episode for OCD at time of NEO-FFI completion. Participants were followed for up to 3 years.
Results suggest individuals with OCD had a 21 % likelihood of reaching remission over the course of 3 years. Greater OCD symptom severity and longer illness duration were associated with a decreased likelihood of remission. Among the five factors of personality, only low extraversion was associated with a decreased rate of remission. Neuroticism, openness, agreeableness, and conscientiousness were not associated with remission.
As this was an observational study, treatment was not controlled precluding examination of treatment on course. Further, data collected on age of onset and symptom severity during follow up were retrospective and therefore are also subject to recall bias.
Our findings provide preliminary support that personality traits are potential factors impacting course and symptom presentation. Future research is necessary to determine the mechanisms in which personality traits may influence the presentation and course of OCD.
个性特征可能使人易患精神病理学。然而,很少有研究探讨个性特征与强迫症(OCD)病程之间的关系。本研究调查了个性特征、OCD 症状严重程度和疾病持续时间作为 OCD 缓解的预测因素。
166 名接受 OCD 治疗的成年人作为布朗纵向强迫症研究的一部分被招募,在完成 NEO 五因素量表 3(NEO-FFI)时处于 OCD 发作期。参与者最多随访 3 年。
结果表明,在 3 年内,OCD 患者达到缓解的可能性为 21%。OCD 症状严重程度越高和疾病持续时间越长,缓解的可能性越低。在个性的五个因素中,只有低外向性与缓解率降低有关。神经质、开放性、宜人性和尽责性与缓解无关。
由于这是一项观察性研究,因此治疗未得到控制,无法检查治疗对病程的影响。此外,在随访期间收集的发病年龄和症状严重程度的数据是回顾性的,因此也存在回忆偏倚。
我们的发现初步支持个性特征是影响 OCD 病程和症状表现的潜在因素。需要进一步研究以确定个性特征可能影响 OCD 表现和病程的机制。