Egashira Shuhei, Doijiri Ryosuke, Endo Hideaki, Kimura Naoto, Nakajima Yoshifumi, Morino Yoshihiro, Kikuchi Takahiko
Department of Neurology, Iwate Prefectural Central Hospital.
Department of Cerebrovascular Medicine and Neurology, National Cerebral and Cardiovascular Center.
Rinsho Shinkeigaku. 2022 Oct 22;62(10):787-792. doi: 10.5692/clinicalneurol.cn-001781. Epub 2022 Sep 30.
A 61-year-old man presented with transient dysarthria and left upper extremity numbness. Head MRI showed an acute infarct in the left temporal lobe and multiple old infarcts in the bilateral cortices. A transesophageal echocardiogram revealed a patent foramen ovale with a large shunt. No deep vein thrombosis was found. He suffered a recurrent cerebral infarction while taking antiplatelet therapy. An insertable cardiac monitor was implanted on the 41st day, and the antiplatelet treatment was changed to warfarin. The insertable cardiac monitor did not detect atrial fibrillation, even when the patient had a recurrent transient ischemic attack on the 57th day under warfarin therapy. The patient underwent percutaneous foramen ovale closure on the 63rd day. On postoperative days 18-25, an insertable cardiac monitor detected brief atrial fibrillation, and he took rivaroxaban for three months. Atrial fibrillation may occur secondary to percutaneous patent foramen ovale closure for cryptogenic stroke. The insertable cardiac monitor may help diagnose the pathogenesis of secondary atrial fibrillation and determine the optimal antithrombotic therapy.
一名61岁男性出现短暂性构音障碍和左上肢麻木。头部MRI显示左侧颞叶急性梗死以及双侧皮质多发陈旧性梗死。经食管超声心动图显示卵圆孔未闭且有大量分流。未发现深静脉血栓形成。他在接受抗血小板治疗时发生了复发性脑梗死。在第41天植入了可插入式心脏监测器,并将抗血小板治疗改为华法林。即使在华法林治疗期间患者于第57天发生复发性短暂性脑缺血发作时,可插入式心脏监测器也未检测到房颤。患者在第63天接受了经皮卵圆孔封堵术。术后第18 - 25天,可插入式心脏监测器检测到短暂房颤,他服用利伐沙班三个月。对于不明原因卒中,经皮卵圆孔封堵术后可能继发房颤。可插入式心脏监测器可能有助于诊断继发性房颤的发病机制并确定最佳抗栓治疗方案。