Department of Experimental and Clinical Biomedical Sciences "M. Serio", University of Florence, Viale Morgagni 50, 50134, Florence, Italy.
Radiation Oncology Unit, Oncology Department, Azienda Ospedaliero Universitaria Careggi, Viale Morgagni 50, 50134, Florence, Italy.
Radiol Med. 2022 Dec;127(12):1407-1411. doi: 10.1007/s11547-022-01563-9. Epub 2022 Oct 6.
Recent advances in non-metastatic breast cancer radiation therapy significantly reshaped our views on modern dose and fractionation schedules. Especially the advent of hypofractionation and partial breast irradiation defined a new concept of treatment optimization, that should strongly include both patient and tumour characteristics in the physician's decision-making process. Unfortunately, hypofractionation for breast cancer radiation therapy needed long time to enter the routine practice during the last decades despite the level-1 evidence published over time. Hereby we present the Italian Association for Radiotherapy and Clinical Oncology (AIRO) Breast Cancer Group position statements for postoperative breast cancer radiation therapy volume, dose, and fractionation to harmonically boost routine clinical practice implementation following evidence-based data.
近年来，非转移性乳腺癌放射治疗的进展显著改变了我们对现代剂量和分割方案的看法。特别是分次照射和部分乳房照射的出现，定义了治疗优化的新概念，这一概念应在医生的决策过程中强烈考虑患者和肿瘤的特征。不幸的是，尽管随着时间的推移发表了 1 级证据，但在过去几十年中，乳腺癌放射治疗的分次照射仍需要很长时间才能进入常规实践。在此，我们提出了意大利放射治疗和临床肿瘤学协会（AIRO）乳腺癌小组关于术后乳腺癌放射治疗体积、剂量和分割的立场声明，以根据循证数据协调促进常规临床实践的实施。
