Carsuzaa Florent, Verillaud Benjamin, Marcy Pierre-Yves, Herman Philippe, Dufour Xavier, Favier Valentin, Thariat Juliette
Department of Oto-Rhino-Laryngology-Head and Neck Surgery, University Hospital of Poitiers, Poitiers, France.
Laboratoire Inflammation, Tissus Epithéliaux et Cytokines (LITEC), University of Poitiers, Poitiers, France.
Front Oncol. 2022 Sep 20;12:1013801. doi: 10.3389/fonc.2022.1013801. eCollection 2022.
In sinonasal cancer surgery, a fundamental challenge is to understand the postoperative imaging changes after reconstruction. Misinterpretation of post-operative imaging may lead to a misdiagnosis of tumor recurrence. Because radiotherapy planning is based on imaging, there are many gaps in knowledge to be filled in the interpretation of postoperative imaging to properly define radiotherapy tumor volumes in the presence of flaps. On the other hand, radiotherapy may be responsible for tissue fibrosis or atrophy, the anatomy of the reconstructed region and the functional outcomes may change after radiotherapy compared to surgery alone. This narrative review illustrates the interdisciplinary aims and challenges of sinonasal reconstructive surgery using flaps or grafts. It is particularly relevant to radiologists and radiation oncologists, at a time when intensity modulated radiotherapy and proton therapy have the potential to further contribute to reduction of morbidity.
在鼻窦癌手术中,一个基本挑战是理解重建后的术后影像变化。对术后影像的错误解读可能导致肿瘤复发的误诊。由于放射治疗计划基于影像,在存在皮瓣的情况下,术后影像解读方面有许多知识空白有待填补,以便正确界定放射治疗的肿瘤体积。另一方面,放射治疗可能导致组织纤维化或萎缩,与单纯手术相比,放射治疗后重建区域的解剖结构和功能结果可能会发生变化。这篇叙述性综述阐述了使用皮瓣或移植物进行鼻窦重建手术的跨学科目标和挑战。在调强放射治疗和质子治疗有可能进一步降低发病率之际,这对放射科医生和放射肿瘤学家尤为重要。