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《中国抗中性粒细胞胞浆抗体相关性血管炎诊断和治疗推荐》

[Recommendations on the diagnosis and treatment of anti-neutrophil cytoplasmic antibody associated vasculitis in China].

作者信息

Tian X P, Zhao L K, Jiang Z Y, Wang Y, Huang C B, Zhao Yan

机构信息

Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, National Clinical Research Center for Dermatologic and Immunologic Diseases, Ministry of Science & Technology, State Key Laboratory of Complex Severe and Rare Diseases, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Beijing 100730, China.

Department of Rheumatology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China.

出版信息

Zhonghua Nei Ke Za Zhi. 2022 Oct 1;61(10):1128-1135. doi: 10.3760/cma.j.cn112138-20220318-00191.

Abstract

Anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV) is a group of systemic small vasculitis characterized by ANCA positive in serum. Three diseases are included in this group of diseases: granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA) and eosinophilic granulomatosis with polyangiitis (EGPA). In China, standardized diagnosis and treatment of AAV is still lacking. Based on the evidence and guidelines from China and abroad, the Chinese Rheumatology Association formulated the standardization of diagnosis and treatment of ANCA associated vasculitis. The purpose is to standardize the diagnosis of AAV and disease activity assessment, and recommend the treatment strategies.

摘要

抗中性粒细胞胞浆抗体(ANCA)相关性血管炎(AAV)是一组以血清ANCA阳性为特征的系统性小血管炎。该组疾病包括三种疾病:肉芽肿性多血管炎(GPA)、显微镜下多血管炎(MPA)和嗜酸性肉芽肿性多血管炎(EGPA)。在中国,AAV仍缺乏标准化的诊断和治疗。基于国内外的证据和指南,中华医学会风湿病学分会制定了ANCA相关性血管炎的诊断和治疗规范。目的是规范AAV的诊断和疾病活动度评估,并推荐治疗策略。

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