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在经皮CT引导下对大肾癌进行冷冻消融术前给予马来酸舒尼替尼:一例报告。

Sunitinib maleate administration before percutaneous CT-guided cryoablation for large renal cell carcinoma: A case report.

作者信息

Nishizawa Kaori, Katsumori Tetsuya, Kotera Yuya, Yoshikawa Tatsuya, Nishimura Tomoaki

机构信息

Department of Radiology, Saiseikai Shiga Hospital, Ohashi 2-4-1, Ritto, Shiga, 520-3046, Japan.

Department of Radiology, Matsushita Memorial Hospital, Sotozima 5-55, Moriguchi, Osaka, 570-8540, Japan.

出版信息

Radiol Case Rep. 2022 Oct 8;17(12):4834-4837. doi: 10.1016/j.radcr.2022.09.047. eCollection 2022 Dec.

Abstract

A 60-year-old woman taking anti-platelet drugs was referred to the hospital for the treatment of advanced renal cell carcinoma. CT revealed that the tumor had a diameter of 5 cm and hyper-vascularity. Percutaneous CT-guided cryoablation (CA) was indicated. Since preprocedural arterial embolization failed to provide sufficient embolic effects, sunitinib maleate was administered. It provided good tumor devascularization and volume reduction, which corresponded to downstage. Therefore, the administration contributed to successfully performing subsequent percutaneous CT-guided CA with no serious hemorrhagic complications. Sunitinib maleate may be an alternative to conventional treatments before CA for renal cell carcinoma.

摘要

一名正在服用抗血小板药物的60岁女性因晚期肾细胞癌被转诊至我院治疗。CT显示肿瘤直径为5 cm且血供丰富。遂行CT引导下经皮冷冻消融术(CA)。由于术前动脉栓塞未能达到充分的栓塞效果,给予马来酸舒尼替尼治疗。其使肿瘤血供良好减少且体积缩小,相当于降期。因此,该药物有助于后续成功实施CT引导下经皮CA,且未出现严重出血并发症。马来酸舒尼替尼可能是肾细胞癌CA术前传统治疗的替代方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c06/9552030/0ba148cfaf7c/gr1.jpg

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