夏季至冬季血压变化与采用随机尿样估算的24小时盐排泄量之间的关系：新潟健康研究

Relationship between changes in blood pressure from summer to winter and estimated 24-hour salt excretion using spot urine: the Niigata Wellness Study.

作者信息

Kato Kiminori, Ishigami Tomoaki, Kobayashi Takashi, Tahiro Minoru, Tashiro Shigemi, Yamada Takaho, Iwanaga Midori, Kodama Satoru, Fujihara Kazuya, Sato Koji, Sone Hirohito

机构信息

Department of Prevention of Noncommunicable Diseases and Promotion of Health Checkup, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Chuoh-ku, Niigata, 951-8510, Japan.

Niigata Association of Occupational Health, 1185-3 Kitaba, Nisi-ku, Niigata, 950-1187, Japan.

出版信息

Hypertens Res. 2023 Jan;46(1):226-230. doi: 10.1038/s41440-022-01049-1. Epub 2022 Oct 16.

DOI:10.1038/s41440-022-01049-1

PMID:36243761

Abstract

A convenient way to determine salt intake is salt excretion using spot urine (e-NaCl). We measured e-NaCl at health checkups and compared results with seasonal changes in blood pressure. Among 19,732 examinees who underwent health checkups from Aug. 2012 to Mar. 2013, age, body weight and e-NaCl were measured and compared to monthly mean systolic blood pressure (SBP). Excluded were those taking antihypertensive drugs and with creatinine levels higher than 2.0 mg/dL. Also examined was salt intake (i-NaCl) by an interview survey from Aug. to Dec. 2012. Correlations with SBP were R = 0.7718 for age, R = 0.5996 for body weight, R = 0.2498 for i-NaCl and R = 0.9335 for e-NaCl. e-NaCl decreased in summer. It was presumed that the reduced burden on the kidney of salt excretion due to sweating may be related to decreases in blood pressure in summer.

摘要

一种便捷的测定盐摄入量的方法是通过随机尿样测定盐排泄量（尿钠排泄量）。我们在健康检查时测量了尿钠排泄量，并将结果与血压的季节性变化进行比较。在2012年8月至2013年3月接受健康检查的19732名受检者中，测量了年龄、体重和尿钠排泄量，并与每月平均收缩压（SBP）进行比较。排除正在服用降压药以及肌酐水平高于2.0mg/dL的受检者。还通过2012年8月至12月的访谈调查对盐摄入量（摄入钠量）进行了检查。年龄与收缩压的相关性R = 0.7718，体重与收缩压的相关性R = 0.5996，摄入钠量与收缩压的相关性R = 0.2498，尿钠排泄量与收缩压的相关性R = 0.9335。尿钠排泄量在夏季减少。据推测，由于出汗导致肾脏排泄盐分的负担减轻，这可能与夏季血压下降有关。