Takayama H, Kazahaya Y, Kashihara N, Kuroda H, Miyawaki S, Ota Z, Ogawa N
J Neurol Neurosurg Psychiatry. 1987 Jul;50(7):915-8. doi: 10.1136/jnnp.50.7.915.
A 24 year old female presented with signs and symptoms of postganglionic cholinergic autonomic dysfunction manifested by impaired lachrymation and salivation, mydriasis of the pupil, decreased gastrointestinal motility, atony of the bladder, and sweating and taste disturbance. Clinical and pharmacological studies confirmed that the abnormalities were restricted mainly to the postganglionic cholinergic autonomic systems. The titre of serum complement was low, antinuclear antibodies revealed a diffuse pattern, and anti SS-A antibody was positive, suggesting that this disorder was caused by an immune mechanism.
一名24岁女性出现节后胆碱能自主神经功能障碍的体征和症状,表现为泪液分泌和唾液分泌受损、瞳孔散大、胃肠蠕动减弱、膀胱张力缺乏以及出汗和味觉障碍。临床和药理学研究证实,这些异常主要局限于节后胆碱能自主神经系统。血清补体滴度较低,抗核抗体呈弥漫性模式,抗SS - A抗体呈阳性,提示该疾病由免疫机制引起。