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类风湿性关节炎膝关节镜下滑膜切除术疗效评估:12至24个月的结果

An evaluation of the efficacy of arthroscopic synovectomy of the knee in rheumatoid arthritis: 12-24 month results.

作者信息

Cohen S, Jones R

出版信息

J Rheumatol. 1987 Jun;14(3):452-5.

PMID:3625627
Abstract

Nine patients with rheumatoid arthritis (10 knees) with chronic knee synovitis unresponsive to medical therapy were entered into a prospective study of arthroscopic total synovectomy of the knee. Histopathological examination of the synovium revealed a proliferative synovitis in all knees. Patients were ambulatory and exhibited 90 degrees of knee flexion on the day after surgery and were discharged at 24 to 48 h postoperation. Mean joint tenderness and swelling improved from the preoperative level and was maintained for the initial 12 months of the study. Knee range of movement was improved in all patients (mean 21 degrees). Improvement of joint function in daily activities was also demonstrated, but patients with Grade IV articular cartilage damage failed to show significant improvement. Nine knees were followed for at least 24 months and 4 required repeat surgery. Arthroscopic synovectomy is comparable to synovectomy by arthrotomy in short term reduction of pain and swelling. The chief benefit of arthroscopic synovectomy is a reduction in morbidity, hospital stay and postoperative rehabilitation.

摘要

9例类风湿性关节炎患者(10个膝关节)患有慢性膝关节滑膜炎,药物治疗无效,进入膝关节关节镜下全滑膜切除术的前瞻性研究。滑膜组织病理学检查显示所有膝关节均为增生性滑膜炎。患者术后第一天可下床活动,膝关节屈曲达90度,术后24至48小时出院。平均关节压痛和肿胀较术前有所改善,并在研究的最初12个月内保持。所有患者的膝关节活动范围均有改善(平均21度)。日常活动中的关节功能也得到改善,但IV级关节软骨损伤患者未显示出明显改善。9个膝关节随访至少24个月,4个需要再次手术。关节镜下滑膜切除术在短期减轻疼痛和肿胀方面与切开滑膜切除术相当。关节镜下滑膜切除术的主要益处是降低发病率、缩短住院时间和减少术后康复时间。

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