Zbären P, Schreiber B, Lehmann W, Widgren S
Laryngol Rhinol Otol (Stuttg). 1987 Jun;66(6):320-3.
Between 1972 and 1985, eleven cases of acinic cell carcinoma were treated at the ENT clinic of the University Hospital Geneva. Eight of them were located in the parotid gland, three in minor salivary glands, two of these on the hard palate and one on the lower lip. Local recurrence occurred in four cases: two were recurrences of a parotid gland carcinoma and two of a minor salivary gland carcinoma. Three patients developed metastases, two in cervical lymph nodes and one in the lungs. Two tumours presented a very aggressive local development. Hence, the acinic cell carcinoma has a significant tendency to recur, to produce metastases, and may have an aggressive evolution. Radical treatment by surgery is necessary.
1972年至1985年间,日内瓦大学医院耳鼻喉科诊所共治疗了11例腺泡细胞癌。其中8例位于腮腺,3例位于小唾液腺,其中2例位于硬腭,1例位于下唇。4例出现局部复发:2例为腮腺癌复发,2例为小唾液腺癌复发。3例患者发生转移,2例转移至颈部淋巴结,1例转移至肺部。2例肿瘤呈现出非常侵袭性的局部发展。因此,腺泡细胞癌有显著的复发、转移倾向,且可能有侵袭性进展。手术根治性治疗是必要的。