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硬膜外穿刺后头痛对剖宫产术后既往存在及新发头痛的影响:一项回顾性研究。

The effect of postdural puncture headache on pre-existing and new-onset headaches after cesarean section: A retrospective study.

作者信息

Bakır Mesut, Rumeli Şebnem, Özge Aynur, Türkyılmaz Gülçin Gazioğlu

机构信息

Division of Algology, Mersin City Education and Research Hospital, Mersin, Turkey.

Division of Algology, Mersin University Faculty of Medicine, Mersin, Turkey.

出版信息

Heliyon. 2022 Oct 10;8(10):e11014. doi: 10.1016/j.heliyon.2022.e11014. eCollection 2022 Oct.

Abstract

BACKGROUND

Obstetric patients are at higher risk of postdural puncture headache (PDPH) than other age- and sex-matched individuals. The debate over the long-term effects of PDPH continues. In this study, we aimed to assess the development of new-onset headaches or worsening of pre-existing chronic headaches in patients who underwent cesarean section under spinal anesthesia and developed PDPH.

METHODS

Forty patients who developed PDPH (Group P) after cesarean section surgery (post-cesarean section-PCS), 80 patients who underwent cesarean section under spinal anesthesia (Group S), and 80 patients who underwent cesarean section under general anesthesia (Group G) were evaluated in the study. Chronic headache and other related symptoms that were present before pregnancy (pre-gestational-PG) and within 12 months after cesarean section were assessed.

RESULTS

Eight of the 40 patients in Group P had a new-onset chronic headache after cesarean surgery, which was significantly higher than the rates in the other groups (p = 0.001). Of the patients whose pre-existing headache worsened during the PCS period, seven were in Group P, and four were in Group S (p = 0.020), while none was in Group G. According to the multiple logistic regression analysis, the risk of worsening headache increased by 1.51-fold for every 1 unit increase in the PG Numerical Rating Scale (NRS).

CONCLUSION

In conclusion, patients who develop PDPH appear to be at higher risk of developing new-onset headaches or worsening of pre-existing headaches compared with those who do not. We believe that keeping a headache diary for patients who will undergo dural puncture for whatever purpose, and also long-term follow-up of these patients for the risk of chronic headaches may increase awareness of this issue.

摘要

背景

与其他年龄和性别匹配的个体相比,产科患者发生硬膜外穿刺后头痛(PDPH)的风险更高。关于PDPH长期影响的争论仍在继续。在本研究中,我们旨在评估在脊髓麻醉下接受剖宫产并发生PDPH的患者中新发头痛或既往慢性头痛恶化的情况。

方法

本研究评估了40例剖宫产手术后发生PDPH的患者(P组)、80例在脊髓麻醉下接受剖宫产的患者(S组)和80例在全身麻醉下接受剖宫产的患者(G组)。评估了妊娠前(孕前-PG)和剖宫产后12个月内存在的慢性头痛及其他相关症状。

结果

P组40例患者中有8例在剖宫产术后出现新发慢性头痛,显著高于其他组(p = 0.001)。在PCS期间,既往头痛加重的患者中,P组有7例,S组有4例(p = 0.020),而G组无。根据多因素logistic回归分析,PG数字评定量表(NRS)每增加1个单位,头痛加重的风险增加1.51倍。

结论

总之,与未发生PDPH的患者相比,发生PDPH的患者似乎有更高的风险出现新发头痛或既往头痛恶化。我们认为,无论出于何种目的接受硬膜穿刺的患者记录头痛日记,并对这些患者进行慢性头痛风险的长期随访,可能会提高对该问题的认识。

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