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腹腔镜单孔与迷你腹腔镜子宫切除术:一项国际研究。

Laparoscopic Single-Port versus Mini-Laparoscopic Hysterectomy: An International Study.

作者信息

Delgado-Sánchez Elsa, Fanfani Francesco, Malzoni Mario, Couso Aldina, Zapico Álvaro, Bogliolo Stefano, Sánchez-Torres Damián A, Gardella Bárbara, Thuissard-Vasallo Israel J, Zapardiel Ignacio

机构信息

Gynecologic Oncology Unit, La Paz University Hospital, Madrid, Spain.

Gynecology Department, University "Gabriele d'Annunzio", Chieti, Italy.

出版信息

Gynecol Obstet Invest. 2022;87(6):381-388. doi: 10.1159/000526834. Epub 2022 Oct 21.

Abstract

OBJECTIVES

Laparoendoscopic single-site surgery (LESS) and mini-laparoscopic surgery (Mini-LPS) have been performed with comparable results to conventional laparoscopy. However, there are few data on the comparison between them. Our main objective was to compare LESS and Mini-LPS in terms of surgical time, postoperative pain, and hospital stay in patients who underwent hysterectomy for benign pathology.

DESIGN

It is a retrospective international multicentric study carried out in 5 centers including 2 Spanish and 3 Italian.

METHODS

Data from patients who underwent hysterectomy for benign pathology between January 1, 2010, and December 31, 2015, were reviewed. We collected the clinical-pathological characteristics of the patients and the perioperative results. The main variables of the study were surgical time, the switch to oral analgesia, and the hospital stay. The two comparison groups in the study included patients undergoing hysterectomy for benign pathology by LESS or by Mini-LPS. The decision to perform the type of procedure was left to the discretion of the surgeon, based primarily on the surgical skills and experience of the center. All data were collected retrospectively by an online encrypted platform.

RESULTS

161 patients were included in the study. 104 (64.6%) patients underwent LESS hysterectomy and 57 (35.4%) Mini-LPS. Median surgical time was significantly longer in the LESS group when compared to the Mini-LPS group (120 vs. 75 min, respectively; p < 0.001). Moreover, longer median hospital stay was observed in the LESS group compared to Mini-LPS (48 vs. 36 h, respectively; p < 0.001). Conversion of the technique to conventional LPS was performed in 4 (2.5%) patients, all of them in the Mini-LPS group (p = 0.015).

LIMITATIONS

It is a retrospective study with the biases that this implies. Furthermore, some variables have been incompletely registered in the database, which implies loss of information. This is a nonrandomized study since the decision to intervene with one or another technique was made by the surgeon, which generated 2 nonhomogeneous groups in terms of the number of patients. On the other hand, all the patients who underwent Mini-LPS hysterectomy belonged to the same center, which may have made these results center dependent.

CONCLUSIONS

Significant shorter surgical time and shorter hospital stay were observed in patients undergoing Mini-LPS hysterectomy compared to LESS technique; however, intraoperative complications related to instrumentation flaws were higher in the mini-LPS group that required conversion to standard laparoscopy in all cases. Both ultra-minimally invasive techniques seem safe to perform hysterectomies for benign pathology and emphasize the importance in surgical training to adapt them to our current practice.

摘要

目的

腹腔镜单孔手术(LESS)和迷你腹腔镜手术(Mini-LPS)的手术效果已与传统腹腔镜手术相当。然而,关于两者之间比较的数据较少。我们的主要目的是比较LESS和Mini-LPS在因良性病变接受子宫切除术患者中的手术时间、术后疼痛及住院时间。

设计

这是一项回顾性国际多中心研究,在包括2个西班牙中心和3个意大利中心的5个中心开展。

方法

回顾2010年1月1日至2015年12月31日期间因良性病变接受子宫切除术患者的数据。我们收集了患者的临床病理特征及围手术期结果。研究的主要变量为手术时间、改用口服镇痛药情况及住院时间。研究中的两个比较组包括通过LESS或Mini-LPS因良性病变接受子宫切除术的患者。手术方式的选择由外科医生自行决定,主要依据中心的手术技能和经验。所有数据通过在线加密平台进行回顾性收集。

结果

161例患者纳入研究。104例(64.6%)患者接受LESS子宫切除术,57例(35.4%)接受Mini-LPS。与Mini-LPS组相比,LESS组的中位手术时间显著更长(分别为120分钟和75分钟;p<0.001)。此外,与Mini-LPS组相比,LESS组的中位住院时间更长(分别为48小时和36小时;p<0.001)。4例(2.5%)患者手术技术转为传统腹腔镜手术,均在Mini-LPS组(p=0.015)。

局限性

这是一项存在相关偏倚的回顾性研究。此外,一些变量在数据库中的记录不完整,这意味着信息丢失。这是一项非随机研究,因为采用何种技术进行干预由外科医生决定,这导致两组患者数量不均一。另一方面,所有接受Mini-LPS子宫切除术的患者均来自同一中心,这可能使这些结果依赖于该中心。

结论

与LESS技术相比,接受Mini-LPS子宫切除术的患者手术时间显著更短,住院时间更短;然而,Mini-LPS组与器械缺陷相关的术中并发症更高,所有病例均需转为标准腹腔镜手术。两种超微创手术方式在因良性病变行子宫切除术中似乎都是安全的,并强调了手术培训以使其适应我们当前实践的重要性。

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