一例伴有多种血栓形成和出血性疾病的先天性纤维蛋白原血症
A case of congenital afibrinogenemia with multiple thrombotic and hemorrhagic disorders.
作者信息
Wei Lijian, Tang Yuting, Wu Zhuohua, Xu Pingyi, Mo Mingshu
机构信息
Department of Neurology the First Affiliated Hospital of Guangzhou Medical University Guangzhou China.
出版信息
Clin Case Rep. 2022 Oct 20;10(10):e6395. doi: 10.1002/ccr3.6395. eCollection 2022 Oct.
Abstract
This is a case of congenital afibrinogenemia with multiple thrombotic and hemorrhagic events. His fibrinogen concentration was negatively correlated with thrombin time and prothrombin time and abnormally negatively correlated with plasma D-dimer levels. The individualized standard for fibrinogen concentration may help to balance thrombotic and hemorrhagic events for this disease.
摘要
这是一例伴有多次血栓形成和出血事件的先天性纤维蛋白原血症病例。其纤维蛋白原浓度与凝血酶时间和凝血酶原时间呈负相关，与血浆D - 二聚体水平呈异常负相关。纤维蛋白原浓度的个体化标准可能有助于平衡该疾病的血栓形成和出血事件。
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