脑脊液中α1-酸性糖蛋白的诊断价值

[Diagnostic value of alpha 1-acid glycoprotein in the cerebrospinal fluid].

作者信息

Linke E, Krause H, Zimmermann K, Grützmann K

出版信息

Psychiatr Neurol Med Psychol (Leipz). 1987 May;39(5):257-66.

Abstract

Samples from 1415 neurological patients were used to study the diagnostic value of acid alpha 1-glycoprotein in the lumbar cerebrospinal fluid. The value of analysis for this substance is considered to lie in the detection of non-specific acute-phase reactions of various causes in the CNS with special reference to barrier problems. The large number of pathologically elevated values associated with acute inflammations of the meninges and cerebral parenchyme is particularly striking. The results of the studies are analyzed on the basis of comprehensive control investigations (n = 559).

摘要

来自1415名神经科患者的样本被用于研究酸性α1-糖蛋白在腰椎脑脊液中的诊断价值。对该物质进行分析的价值在于检测中枢神经系统各种原因引起的非特异性急性期反应，特别是与屏障问题有关的反应。与脑膜和脑实质急性炎症相关的大量病理性升高值尤为显著。研究结果在综合对照研究（n = 559）的基础上进行分析。

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