帕金森病对初次全膝关节置换术结果的影响。
The impact of Parkinson's disease on results of primary total knee arthroplasty.
作者信息
Rodríguez-Merchán E Carlos, Kalbakdij-Sánchez Carlos
机构信息
Department of Orthopaedic Surgery, La Paz University Hospital, Madrid, Spain.
Osteoarticular Surgery Research, Hospital La Paz Institute for Health Research - IdiPAZ (La Paz University Hospital - Autonomous University of Madrid), Madrid, Spain.
出版信息
EFORT Open Rev. 2022 Oct 26;7(10):701-709. doi: 10.1530/EOR-22-0055.
Parkinson's disease (PD) is a common neurodegenerative disorder. When patients with PD undergo total knee arthroplasty (TKA) for knee osteoarthritis, poorer knee function and poorer quality of life are obtained than in matched cohorts (MCs). However, the degree of patient satisfaction is usually high. The mean length of stay is 6.5% longer in patients with PD than in MCs. Compared with MCs, patients with PD undergoing TKA have a 44% higher risk of complications. In patients with PD, the overall complication rate is 26.3% compared with 10.5% in MCs; the periprosthetic joint infection rate is 6.5% in patients with PD vs 1.7% in MCs; and the periprosthetic fracture rate is 2.1% in patients with PD vs 1.7% in MCs. The 90-day readmission rate is 16.29% in patients with PD vs 12.66% in MCs. More flexion contractures occur in patients with PD. The rate of medical complications is 4.21% in patients with PD vs 1.24% in MCs, and the rate of implant-related complications is 5.09% in patients with PD vs 3.15% in MCs. At 5.3 years' mean follow-up, the need for revision surgery is 23.6%. The 10-year implant survival, taking revision of any of the components as an endpoint, is 89.7% in patients with PD vs 98.3% in MCs.
帕金森病（PD）是一种常见的神经退行性疾病。当帕金森病患者因膝关节骨关节炎接受全膝关节置换术（TKA）时，与匹配队列（MCs）相比，其膝关节功能更差，生活质量更低。然而，患者的满意度通常较高。帕金森病患者的平均住院时间比匹配队列长6.5%。与匹配队列相比，接受全膝关节置换术的帕金森病患者发生并发症的风险高44%。在帕金森病患者中，总体并发症发生率为26.3%，而匹配队列中为10.5%；假体周围关节感染率在帕金森病患者中为6.5%，而匹配队列中为1.7%；假体周围骨折率在帕金森病患者中为2.1%，而匹配队列中为1.7%。帕金森病患者的90天再入院率为16.29%，而匹配队列中为12.66%。帕金森病患者发生更多的屈曲挛缩。帕金森病患者的医疗并发症发生率为4.21%，而匹配队列中为1.24%，与植入物相关的并发症发生率在帕金森病患者中为5.09%，而匹配队列中为3.15%。在平均5.3年的随访中，翻修手术的需求率为23.6%。以任何部件的翻修为终点，帕金森病患者10年的植入物生存率为89.7%，而匹配队列中为98.3%。
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