Yoo Jeong Min, Mendoza Remilyn M, Hwang In-Chan, Kang Dae-Kyung
Department of Animal Resources Science, Dankook University, Cheonan 31116, Korea.
J Anim Sci Technol. 2022 Sep;64(5):1008-1011. doi: 10.5187/jast.2022.e55. Epub 2022 Sep 30.
We here report the whole genome sequence of C7 with anti-listerial activity, which was isolated from pig feces. The genome size of C7 (~ 3.0 Mb) is relatively larger compared with other strains. C7 carries three bacteriocin gene clusters encoding garvicin Q, salivaricin A, and Blp family class II bacteriocin. Garvicin Q and salivaricin A are reported to be active against and , respectively, as well as against other Gram-positive bacteria. Meanwhile, the bacteriocin encoded in the cassette was shown to be active against pneumococci, mediating intraspecies competition. This report highlights the potential of C7 for the production of bacteriocins inhibiting pathogenic bacteria.
我们在此报告从猪粪便中分离出的具有抗李斯特菌活性的C7的全基因组序列。与其他菌株相比，C7的基因组大小（约3.0 Mb）相对较大。C7携带三个细菌素基因簇，分别编码加维菌素Q、唾液乳杆菌素A和Blp家族II类细菌素。据报道，加维菌素Q和唾液乳杆菌素A分别对[此处原文缺失相关细菌名称]以及其他革兰氏阳性菌具有活性。同时，盒式结构中编码的细菌素对肺炎球菌具有活性，可介导种内竞争。本报告突出了C7在生产抑制病原菌的细菌素方面的潜力。
