Heidet Matthieu, Freyssenge Julie, Claustre Clément, Deakin John, Helmer Jennie, Thomas-Lamotte Bruno, Wohl Mathys, Danny Liang Li, Hubert Hervé, Baert Valentine, Vilhelm Christian, Fraticelli Laurie, Mermet Éric, Benhamed Axel, Revaux François, Lecarpentier Éric, Debaty Guillaume, Tazarourte Karim, Cheskes Sheldon, Christenson Jim, El Khoury Carlos, Grunau Brian
Assistance Publique - Hôpitaux de Paris (AP-HP), SAMU 94 and Emergency Department, Hôpitaux universitaires Henri Mondor, Créteil, France; Université Paris-Est Créteil (UPEC), EA-3956 (Control in Intelligent Networks [CIR]), Créteil, France.
Université Claude Bernard Lyon 1, INSERM U1290, Research on Healthcare Performance (RESHAPE), Lyon, France; Urgences-ARA Network, ARS Auvergne Rhône-Alpes, Lyon, France.
Resuscitation. 2022 Dec;181:97-109. doi: 10.1016/j.resuscitation.2022.10.016. Epub 2022 Oct 26.
To compare walking access times to automated external defibrillators (AEDs) between area-level quintiles of socioeconomic status (SES) in out-of-hospital cardiac arrest (OHCA) cases occurring in 2 major urban regions of Canada and France.
This was an international, multicenter, retrospective cohort study of adult, non-traumatic OHCA cases in the metropolitan Vancouver (Canada) and Rhône County (France) regions that occurred between 2014 and 2018. We calculated area-level SES for each case, using quintiles of country-specific scores (Q5 = most deprived). We identified AED locations from local registries. The primary outcome was the simulated walking time from the OHCA location to the closest AED (continuous and dichotomized by a 3-minute 1-way threshold). We fit multivariate models to analyze the association between OHCA-to-AED walking time and outcomes (Q5 vs others).
A total of 6,187 and 3,239 cases were included from the Metro Vancouver and Rhône County areas, respectively. In Metro Vancouver Q5 areas (vs Q1-Q4), areas, AEDs were farther from (79 % over 400 m from case vs 67 %, p < 0.001) and required longer walking times to (97 % above 3 min vs 91 %, p < 0.001) cases. In Rhône Q5 areas, AEDs were closer than in other areas (43 % over 400 m from case vs 50 %, p = 0.01), yet similarly poorly accessible (85 % above 3 min vs 86 %, p = 0.79). In multivariate models, AED access time ≥ 3 min was associated with decreased odds of survival at hospital discharge in Metro Vancouver (odds ratio 0.41, 95 % CI [0.23-0.74], p = 0.003).
Accessibility of public AEDs was globally poor in Metro Vancouver and Rhône, and even poorer in Metro Vancouver's socioeconomically deprived areas.
比较加拿大和法国两个主要城市地区院外心脏骤停(OHCA)病例中,社会经济地位(SES)处于地区水平五分位数之间,到达自动体外除颤器(AED)的步行时间。
这是一项针对2014年至2018年间在加拿大温哥华市和法国罗纳县发生的成年非创伤性OHCA病例的国际多中心回顾性队列研究。我们使用特定国家分数的五分位数(Q5 = 最贫困)计算每个病例的地区水平SES。我们从当地登记处确定AED的位置。主要结局是模拟从OHCA发生地点到最近AED的步行时间(连续变量,并以3分钟单程阈值进行二分法划分)。我们拟合多变量模型以分析OHCA到AED的步行时间与结局(Q5与其他组)之间的关联。
温哥华市和罗纳县地区分别纳入了6187例和3239例病例。在温哥华市的Q5地区(与Q1 - Q4地区相比),AED距离病例更远(79%距离病例超过400米,而Q1 - Q4地区为67%,p < 0.001),且到达病例所需的步行时间更长(97%超过3分钟,而Q1 - Q4地区为91%,p < 0.001)。在罗纳县的Q5地区,AED比其他地区更近(43%距离病例超过400米,而其他地区为50%,p = 0.01),但同样难以到达(85%超过3分钟,而其他地区为86%,p = 0.79)。在多变量模型中,AED获取时间≥3分钟与温哥华市出院时存活几率降低相关(比值比0.41,95%置信区间[0.23 - 0.74],p = 0.003)。
在温哥华市和罗纳县,公共AED的可及性总体较差,在温哥华市社会经济贫困地区更差。