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在冯·希佩尔-林道综合征背景下,镓-多柔比星亲和性转移性肾细胞癌累及椎体

Ga-DOTATATE Avid Metastatic Vertebral Renal Cell Carcinoma in the Setting of von Hippel-Lindau Syndrome.

作者信息

Patel Mayank, Jha Abhishek, Antic Tatjana, Nielsen Sarah M, Churpek Jane E, Ling Alexander, Pacak Karel

机构信息

Section on Medical Neuroendocrinology, Developmental Endocrine Oncology and Genetics Affinity Group, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, 10 Center Dr., MSC-1109, Bldg. 10, CRC, Room 1E-3140, Bethesda, MD 20892-1109 USA.

Department of Pathology, University of Chicago Medical Center, Chicago, IL USA.

出版信息

Nucl Med Mol Imaging. 2022 Oct;56(5):259-262. doi: 10.1007/s13139-022-00761-7. Epub 2022 Jul 27.

Abstract

Although rare, a metastatic renal cell carcinoma could present with Ga-DOTATATE avidity. A 66-year-old man with von Hippel-Lindau syndrome (VHL) presented with Ga-DOTATATE uptake in the pancreatic head, splenic hilar region, and multiple osseous sites, including the right lateral portion of the T9 vertebrae. Biopsy of the T9 lesion confirmed metastatic renal cell carcinoma. Various VHL-associated cancers may display Ga-DOTATATE avidity, which can change and guide clinical decisions for the patient.

摘要

虽然罕见,但转移性肾细胞癌可能表现出镓[68Ga] DOTATATE摄取。一名患有冯·希佩尔-林道综合征(VHL)的66岁男性,在胰头、脾门区域以及多个骨部位(包括T9椎体右侧部分)出现镓[68Ga] DOTATATE摄取。T9病变的活检证实为转移性肾细胞癌。各种与VHL相关的癌症可能显示镓[68Ga] DOTATATE摄取,这可以改变并指导针对该患者的临床决策。

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