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注意力缺陷多动障碍的家长培训:一项随机对照试验中从临床结果到神经心理学结果的效应无普遍性

Parent Training for ADHD: No Generalization of Effects From Clinical to Neuropsychological Outcomes in a Randomized Controlled Trial.

作者信息

Lambek Rikke, Sonuga-Barke Edmund J S, Lange Anne-Mette, Carroll Daniel J, Daley David, Thomsen Per Hove

机构信息

Aarhus University, Denmark.

King's College London, UK.

出版信息

J Atten Disord. 2023 Jan;27(1):98-107. doi: 10.1177/10870547221130108. Epub 2022 Oct 31.

DOI:10.1177/10870547221130108
PMID:36314486
Abstract

OBJECTIVE

We examined whether neuropsychological function in ADHD can be improved by the New Forest Parenting Programme (NFPP), that combines standard parenting strategies with self-regulatory skills training, or predict ADHD and quality of life (QoL) treatment effects.

METHOD

Participants were 93 medication-naive preschool children with ADHD (3-7 years) randomized to either NFPP ( = 49) or treatment as usual (TAU; = 44) in a recent randomized trial. Laboratory measures of executive function, reaction time variability, and delay of gratification were collected along with parent ratings of ADHD and QoL at baseline and post treatment. Ratings were collected again at 3-month follow-up.

RESULTS

NFPP did not improve neuropsychological function (compared to TAU), and baseline neuropsychological function did not predict treatment-related ADHD or QoL effects.

CONCLUSION

Although NFPP includes a neuropsychological training element and has been shown to improve several clinical outcomes, it did not improve the neuropsychological functions it targets.

摘要

目的

我们研究了将标准育儿策略与自我调节技能训练相结合的新森林育儿计划(NFPP)是否能改善多动症患者的神经心理功能,或者预测多动症及生活质量(QoL)的治疗效果。

方法

在最近一项随机试验中,93名未接受过药物治疗的3至7岁多动症学龄前儿童被随机分为NFPP组(n = 49)或常规治疗组(TAU;n = 44)。在基线和治疗后收集执行功能、反应时间变异性和延迟满足的实验室测量数据,以及家长对多动症和生活质量的评分。在3个月随访时再次收集评分。

结果

与TAU相比,NFPP并未改善神经心理功能,且基线神经心理功能无法预测与治疗相关的多动症或生活质量效果。

结论

尽管NFPP包含神经心理训练元素,且已被证明能改善多种临床结果,但它并未改善其目标神经心理功能。

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