Suppr超能文献

超越类器官实体的道德地位。

Moving beyond the moral status of organoid-entities.

作者信息

Barnhart Andrew J, Dierickx Kris

机构信息

Department of Public Health and Primary Care, Centre for Biomedical Ethics and Law, KU Leuven, Leuven, Belgium.

出版信息

Bioethics. 2023 Feb;37(2):103-110. doi: 10.1111/bioe.13098. Epub 2022 Nov 2.

Abstract

Ethical deliberations are unfolding for potentially controversial organoid-entities such as brain organoids and embryoids. Much of the ethical deliberation centers on the questionable moral status of such organoid-entities. However, while such work is important and appropriate, ethical deliberations may become too exclusively rooted in moral status and potentially overshadow other relevant moral dilemmas. The ethical discussion on organoid models can benefit from insights brought forth by both Judith Jarvis Thomson and Don Marquis in how they attempted to advance the abortion debate. To discuss other abortion ethical issues more fully, both Thomson and Marquis assumed differing moral status positions of the conceptus and followed lines of reasoning based on these moral status assumptions. We suggest a similar approach with controversial organoid-entities like brain organoids and embryoids. To avoid overshadowing or overlooking other relevant ethical issues, ethicists ought to first assume an organoid-entity moral status position (such as a high moral status or no moral status) and explore any possible arguments that may result from such a position. While we ought not to copy the content of Thomson and Marquis' arguments exactly for organoid-entities, it is worthwhile to translate their arguments' overarching structures. This paper explores the relevant insights of Thomson and Marquis, how they can be translated into the organoid ethics debate, and what possible lines of inquiry may be worth exploring based on particular moral status assumptions.

摘要

对于诸如脑类器官和胚状体等可能存在争议的类器官实体,伦理思考正在展开。许多伦理思考都集中在这类类器官实体可疑的道德地位上。然而,尽管此类工作很重要且恰当,但伦理思考可能过于排他地植根于道德地位,并且可能掩盖其他相关的道德困境。关于类器官模型的伦理讨论可以从朱迪思·贾维斯·汤姆森和唐·马奎斯在推进堕胎辩论时提出的见解中受益。为了更全面地讨论其他堕胎伦理问题,汤姆森和马奎斯都对胎儿的道德地位持有不同立场,并基于这些道德地位假设进行推理。我们建议对脑类器官和胚状体等有争议的类器官实体采取类似的方法。为了避免掩盖或忽视其他相关的伦理问题,伦理学家应该首先假设一种类器官实体的道德地位立场(例如高道德地位或无道德地位),并探索这种立场可能产生的任何可能论点。虽然我们不应该完全照搬汤姆森和马奎斯针对类器官实体的论点内容,但值得借鉴他们论点的总体结构。本文探讨了汤姆森和马奎斯的相关见解,它们如何转化为类器官伦理辩论,以及基于特定道德地位假设可能值得探索哪些探究方向。

相似文献

1
Moving beyond the moral status of organoid-entities.
Bioethics. 2023 Feb;37(2):103-110. doi: 10.1111/bioe.13098. Epub 2022 Nov 2.
2
Spontaneous abortion and unexpected death: a critical discussion of Marquis on abortion.
J Med Ethics. 2013 Feb;39(2):89-93. doi: 10.1136/medethics-2012-100604. Epub 2012 Oct 4.
3
The Many Moral Matters of Organoid Models: A systematic review of reasons.
Med Health Care Philos. 2022 Sep;25(3):545-560. doi: 10.1007/s11019-022-10082-3. Epub 2022 May 9.
4
Weighing the moral status of brain organoids and research animals.
Bioethics. 2024 Jun;38(5):410-418. doi: 10.1111/bioe.13290. Epub 2024 Apr 26.
5
Moral status of the fetus and the permissibility of abortion: a contractarian response to Thomson's violinist thought experiment.
J Med Ethics. 2022 Jun;48(6):407-410. doi: 10.1136/medethics-2020-106810. Epub 2021 May 7.
6
Marquis: a defense of abortion?
Bioethics. 2001 Apr;15(2):135-45. doi: 10.1111/1467-8519.00221.
7
Avoiding the Personhood Issue: Abortion, Identity, and Marquis's 'Future-Like-Ours' Argument.
Bioethics. 2016 May;30(4):272-81. doi: 10.1111/bioe.12211. Epub 2015 Sep 30.
8
Cardiac organoids do not warrant additional moral scrutiny.
BMC Med Ethics. 2024 May 21;25(1):61. doi: 10.1186/s12910-024-01064-6.
9
Moral Limits of Brain Organoid Research.
J Law Med Ethics. 2019 Dec;47(4):760-767. doi: 10.1177/1073110519897789.
10
Abortion and the Epicurean challenge.
J Med Ethics. 2020 Apr;46(4):273-274. doi: 10.1136/medethics-2019-105771. Epub 2019 Oct 19.

引用本文的文献

1
Application and prospect of organoid technology in breast cancer.
Front Immunol. 2024 Aug 26;15:1413858. doi: 10.3389/fimmu.2024.1413858. eCollection 2024.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验